About Oruka Therapeutics Inc
- Industry: Biotechnology
- Exchange: NASDAQ NMS - GLOBAL MARKET
- Country: US
- Website: https://orukatx.com/
Frequently Asked Questions
What is the 52-week range for ORKA?
The 52-week high is $115.515 and the 52-week low is $18.19.
What is the P/E ratio for ORKA?
The P/E ratio data is currently unavailable.
What is the dividend yield for ORKA?
This company does not currently pay a dividend or the data is unavailable.
What is the Return on Equity (ROE)?
The trailing twelve months (TTM) Return on Equity is -20.76%.
What is the Net Profit Margin?
The Net Profit Margin (TTM) is -26.27%.
What is the Price to Book (P/B) Ratio?
The annual Price to Book ratio stands at 3.11.
Analyst Recommendation Trends
Wall Street analyst consensus for ORKA over the last few months:
Latest ORKA News
Oruka Therapeutics' Psoriasis Treatment Maintains 'Competitive Profile' After Positive Clinical Data, UBS Says
Oruka Therapeutics' (ORKA) lead program of long-acting IL-23 in moderate-to-severe psoriasis maintai
ORKA Stock Down 5% Despite Positive Week 28 Psoriasis Efficacy Data
Oruka's ORKA-001 delivers deeper psoriasis clearance at week 28, but safety disclosures may have weighed on shares despite positive efficacy data.
Wedbush Reiterates Outperform on Oruka Therapeutics, Maintains $165 Price Target
Wedbush analyst Martin Fan reiterates Oruka Therapeutics (NASDAQ:ORKA) with a Outperform and maintains $165 price target.
HC Wainwright & Co. Reiterates Buy on Oruka Therapeutics, Maintains $120 Price Target
HC Wainwright & Co. analyst Mitchell S. Kapoor reiterates Oruka Therapeutics (NASDAQ:ORKA) with a Buy and maintains $120 price target.
What Oruka Therapeutics (ORKA)'s Phase 2a Psoriasis Data Means For Shareholders
Oruka Therapeutics recently reported positive Week 28 data from its EVERLAST-A Phase 2a trial of ORKA-001 in moderate-to-severe plaque psoriasis, showing deepening clinical responses and a safety profile consistent with the IL-23p19 class. An interesting aspect is that placebo patients who later crossed over to ORKA-001 achieved similar response patterns, underscoring the drug’s potential effect even after delayed initiation. Next, we’ll examine how ORKA-001’s high PASI 100 and PASI 90...
The Biggest Losers In Biotech — And It Had Nothing To Do With 'Compelling,' 'Best-In-Disease' Data
Biotech stocks widely slumped Wednesday, with Rapport Therapeutics, Climb Bio and Cullinan Therapeutics among some of the hardest-hit names.
Oruka Therapeutics Says Psoriasis Drug Shows Deepening Efficacy
Oruka Therapeutics Inc. (NASDAQ:ORKA) on Wednesday reported positive week 28 outcomes from its Phase 2a clinical trial evaluating ORKA-001 for moderate-to-severe plaque psoriasis.The clinical-stage biotechnology firm noted that patient responses improved significantly six months after receiving their final dose of the novel antibody.Phase 2a Trial Demonstrates Deepening EfficacyData showed that 63.5% of treated patients achieved complete skin clearance, or PASI 100, at week 16.Clinical improveme
10 Health Care Stocks Whale Activity In Today’s Session
This whale alert can help traders discover the next big trading opportunities. Whales are entities with large sums of money and we track their transactions here at Benzinga on our options activity scanner. Traders often
Oruka Therapeutics Shares Fall 5% After Week 28 ORKA-001 Trial Data
Oruka Therapeutics, Inc. (NASDAQ:ORKA) shares fell 5% on Wednesday morning after the biotechnology company reported Week 28 results from its EVERLAST-A Phase 2a trial of ORKA-001 in moderate-to-severe plaque psoriasis.
Oruka Therapeutics Announces Positive Week 28 Data for ORKA-001 from the Ongoing EVERLAST-A Trial Showing Deepening of Responses Without Additional Dosing
PASI 100 increased to 71.4% and PASI 90 increased to 87.3%, despite no dosing after Week 4 Placebo crossover patients reached PASI 100 and PASI 90 rates similar to those initially dosed with ORKA-001 ORKA-001 maintained a favorable safety and tolerability profile through Week 28 52-week EVERLAST-A data for all patients expected in December 2026 16-week EVERLAST-B data expected in 4Q 2026 MENLO PARK, Calif., Sept. 23, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a c
Oruka Therapeutics Announces Week 28 Results From Its EVERLAST-A Phase 2A Trial Of ORKA-001 In Moderate-To-Severe Plaque Psoriasis; ORKA-001 Maintained Favorable Safety And Tolerability Profile Through Week 28; 16-Week EVERLAST-B Data Expected In Q4 2026
Week 28 results from its EVERLAST-A Phase 2a trial of ORKA-001, a novel half-life extended IL-23p19 monoclonal antibody, in moderate-to-severe plaque psoriasis."These Week 28 results, with responses continuing to
Oruka Therapeutics to Attend the 2026 Morgan Stanley Global Healthcare Conference
MENLO PARK, Calif., Sept. 09, 2026 (GLOBE NEWSWIRE) -- Oruka Therapeutics, Inc. (“Oruka”) (Nasdaq: ORKA), a clinical-stage biotechnology company developing novel biologics designed to set a new standard for the treatment of chronic skin diseases including plaque psoriasis and hidradenitis suppurativa, today announced its attendance at the 2026 Morgan Stanley Global Healthcare Conference, taking place in New York, NY from September 14-16, 2026.About Oruka TherapeuticsOruka Therapeutics is develop
Related Stocks (Peers)
Recent Insider Transactions
| Date | Name | Shares Changed | Price | Value |
|---|---|---|---|---|
| 2026-09-21 | Agarwal Arjun | -533 | $95.75 | $51,035 |
| 2026-09-21 | Quinlan Paul T | -10,000 | - | - |
| 2026-09-21 | Quinlan Paul T | -2,667 | $95.3115 | $254,196 |
| 2026-09-21 | Quinlan Paul T | -601 | $94.4426 | $56,760 |
| 2026-09-21 | Quinlan Paul T | -3,832 | $93.3173 | $357,592 |
| 2026-09-21 | Quinlan Paul T | -2,900 | $92.3689 | $267,870 |
| 2026-09-21 | Quinlan Paul T | +10,000 | $7.8 | $78,000 |
| 2026-09-15 | Sandler Laura Lee | -906 | $95.71 | $86,713 |
| 2026-09-15 | Agarwal Arjun | -560 | $95.71 | $53,598 |
| 2026-09-15 | Klein Lawrence Otto | -2,452 | $95.71 | $234,681 |
| 2026-09-15 | Goncalves Joana | -3,500 | - | - |
| 2026-09-15 | Goncalves Joana | -3,500 | - | - |
| 2026-09-15 | Goncalves Joana | -947 | $95.71 | $90,637 |
| 2026-09-15 | Goncalves Joana | -100 | $94.2172 | $9,422 |
| 2026-09-15 | Goncalves Joana | -1,366 | $92.9888 | $127,023 |
| 2026-09-15 | Goncalves Joana | -3,150 | $92.0285 | $289,890 |
| 2026-09-15 | Goncalves Joana | -2,384 | $91.0962 | $217,173 |
| 2026-09-15 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-09-15 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-09-15 | Quinlan Paul T | -1,039 | $95.71 | $99,443 |
| 2026-09-11 | Agarwal Arjun | -1,459 | - | - |
| 2026-09-11 | Agarwal Arjun | -8,000 | - | - |
| 2026-09-11 | Agarwal Arjun | -200 | $94.015 | $18,803 |
| 2026-09-11 | Agarwal Arjun | -2,208 | $93.2611 | $205,921 |
| 2026-09-11 | Agarwal Arjun | -4,051 | $92.4135 | $374,367 |
| 2026-09-11 | Agarwal Arjun | -3,000 | $91.1073 | $273,322 |
| 2026-09-11 | Agarwal Arjun | +1,459 | $34.39 | $50,175 |
| 2026-09-11 | Agarwal Arjun | +8,000 | $12.5 | $100,000 |
| 2026-09-01 | Sandler Laura Lee | -5,000 | - | - |
| 2026-09-01 | Sandler Laura Lee | -4,000 | $92.0134 | $368,054 |
| 2026-09-01 | Sandler Laura Lee | -1,000 | $91.0476 | $91,048 |
| 2026-09-01 | Sandler Laura Lee | +5,000 | $7.8 | $39,000 |
| 2026-09-01 | Klein Lawrence Otto | -75,000 | - | - |
| 2026-09-01 | Klein Lawrence Otto | -4,800 | $92.4357 | $443,691 |
| 2026-09-01 | Klein Lawrence Otto | -63,596 | $91.8963 | $5,844,237 |
| 2026-09-01 | Klein Lawrence Otto | -6,604 | $90.7868 | $599,556 |
| 2026-09-01 | Klein Lawrence Otto | +75,000 | $7.8 | $585,000 |
| 2026-08-24 | Edwards Larry Todd | +20,000 | - | - |
| 2026-08-24 | Edwards Larry Todd | +100,000 | - | - |
| 2026-08-17 | Goncalves Joana | -3,500 | - | - |
| 2026-08-17 | Goncalves Joana | -3,500 | - | - |
| 2026-08-17 | Goncalves Joana | -2,480 | $112.5622 | $279,154 |
| 2026-08-17 | Goncalves Joana | -3,320 | $112.0138 | $371,886 |
| 2026-08-17 | Goncalves Joana | -300 | $110.5167 | $33,155 |
| 2026-08-17 | Goncalves Joana | -900 | $109.6522 | $98,687 |
| 2026-08-17 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-08-17 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-08-14 | Quinlan Paul T | -42,000 | - | - |
| 2026-08-14 | Quinlan Paul T | -10,000 | - | - |
| 2026-08-14 | Quinlan Paul T | -3,847 | $111.1378 | $427,547 |
| 2026-08-14 | Quinlan Paul T | -9,193 | $110.0039 | $1,011,266 |
| 2026-08-14 | Quinlan Paul T | -10,200 | $109.1131 | $1,112,954 |
| 2026-08-14 | Quinlan Paul T | -14,696 | $107.9735 | $1,586,779 |
| 2026-08-14 | Quinlan Paul T | -10,434 | $107.1402 | $1,117,901 |
| 2026-08-14 | Quinlan Paul T | -3,630 | $106.0504 | $384,963 |
| 2026-08-14 | Quinlan Paul T | +42,000 | $12.5 | $525,000 |
| 2026-08-14 | Quinlan Paul T | +10,000 | $7.8 | $78,000 |
| 2026-08-13 | Agarwal Arjun | -1,458 | - | - |
| 2026-08-13 | Agarwal Arjun | -8,542 | - | - |
| 2026-08-13 | Agarwal Arjun | -2,358 | $108.4628 | $255,755 |
| 2026-08-13 | Agarwal Arjun | -2,142 | $107.7138 | $230,723 |
| 2026-08-13 | Agarwal Arjun | -1,268 | $106.6255 | $135,201 |
| 2026-08-13 | Agarwal Arjun | -2,132 | $105.5716 | $225,079 |
| 2026-08-13 | Agarwal Arjun | -2,100 | $104.6734 | $219,814 |
| 2026-08-13 | Agarwal Arjun | +1,458 | $34.39 | $50,141 |
| 2026-08-13 | Agarwal Arjun | +8,542 | $12.5 | $106,775 |
| 2026-07-15 | Goncalves Joana | -3,500 | - | - |
| 2026-07-15 | Goncalves Joana | -3,500 | - | - |
| 2026-07-15 | Goncalves Joana | -300 | $87.2533 | $26,176 |
| 2026-07-15 | Goncalves Joana | -3,803 | $86.6764 | $329,630 |
| 2026-07-15 | Goncalves Joana | -2,497 | $85.8572 | $214,385 |
| 2026-07-15 | Goncalves Joana | -400 | $84.365 | $33,746 |
| 2026-07-15 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-07-15 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-07-13 | Agarwal Arjun | -1,458 | - | - |
| 2026-07-13 | Agarwal Arjun | -8,541 | - | - |
| 2026-07-13 | Agarwal Arjun | -300 | $85.6333 | $25,690 |
| 2026-07-13 | Agarwal Arjun | -5,656 | $84.9012 | $480,201 |
| 2026-07-13 | Agarwal Arjun | -3,743 | $84.2557 | $315,369 |
| 2026-07-13 | Agarwal Arjun | -300 | $83.0665 | $24,920 |
| 2026-07-13 | Agarwal Arjun | +1,458 | $34.39 | $50,141 |
| 2026-07-13 | Agarwal Arjun | +8,541 | $12.5 | $106,763 |
| 2026-07-01 | Sandler Laura Lee | -5,000 | - | - |
| 2026-07-01 | Sandler Laura Lee | -500 | $95.472 | $47,736 |
| 2026-07-01 | Sandler Laura Lee | -2,263 | $94.7458 | $214,410 |
| 2026-07-01 | Sandler Laura Lee | -2,237 | $93.8457 | $209,933 |
| 2026-07-01 | Sandler Laura Lee | +5,000 | $7.8 | $39,000 |
| 2026-07-01 | Fairmount Funds Management LLC | -42,641 | - | - |
| 2026-07-01 | Fairmount Funds Management LLC | -3,553,410 | $84.43 | $300,014,406 |
| 2026-07-01 | Fairmount Funds Management LLC | +3,553,410 | - | - |
| 2026-06-22 | Agarwal Arjun | -699 | $82.145 | $57,419 |
| 2026-06-22 | Agarwal Arjun | -888 | $80.01 | $71,049 |
| 2026-06-15 | Quinlan Paul T | -733 | $69.69 | $51,083 |
| 2026-06-15 | Sandler Laura Lee | -600 | $69.69 | $41,814 |
| 2026-06-15 | Agarwal Arjun | -395 | $69.69 | $27,528 |
| 2026-06-15 | Klein Lawrence Otto | -1,729 | $69.69 | $120,494 |
| 2026-06-15 | Goncalves Joana | -3,500 | - | - |
| 2026-06-15 | Goncalves Joana | -3,500 | - | - |
| 2026-06-15 | Goncalves Joana | -947 | $69.69 | $65,996 |
| 2026-06-15 | Goncalves Joana | -300 | $70.6233 | $21,187 |
| 2026-06-15 | Goncalves Joana | -5,064 | $69.4209 | $351,547 |
| 2026-06-15 | Goncalves Joana | -1,636 | $68.3839 | $111,876 |
| 2026-06-15 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-06-15 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-06-12 | Agarwal Arjun | -1,459 | - | - |
| 2026-06-12 | Agarwal Arjun | -8,000 | - | - |
| 2026-06-12 | Agarwal Arjun | -3,260 | $70.3392 | $229,306 |
| 2026-06-12 | Agarwal Arjun | -4,340 | $69.8512 | $303,154 |
| 2026-06-12 | Agarwal Arjun | -1,859 | $68.3419 | $127,048 |
| 2026-06-12 | Agarwal Arjun | +1,459 | $34.39 | $50,175 |
| 2026-06-12 | Agarwal Arjun | +8,000 | $12.5 | $100,000 |
| 2026-06-12 | Dambkowski Carl | -12,583 | $70.109 | $882,182 |
| 2026-06-11 | Dambkowski Carl | -22,417 | $70.1343 | $1,572,201 |
| 2026-06-02 | Martin Christopher Nathan | +9,136 | - | - |
| 2026-06-02 | Dambkowski Carl | +9,136 | - | - |
| 2026-06-02 | Kulkarni Samarth | +9,136 | - | - |
| 2026-06-02 | Fairmount Healthcare Fund II L.P. | +9,136 | - | - |
| 2026-06-02 | BALL KRISTINE M | +9,136 | - | - |
| 2026-05-21 | Dambkowski Carl | -11,667 | - | - |
| 2026-05-21 | Dambkowski Carl | -11,904 | - | - |
| 2026-05-21 | Dambkowski Carl | -38,689 | - | - |
| 2026-05-21 | Dambkowski Carl | -13,235 | $59.9669 | $793,662 |
| 2026-05-21 | Dambkowski Carl | -53,447 | $59.1036 | $3,158,910 |
| 2026-05-21 | Dambkowski Carl | -38,318 | $58.4267 | $2,238,794 |
| 2026-05-21 | Dambkowski Carl | +11,667 | $11.77 | $137,321 |
| 2026-05-21 | Dambkowski Carl | +11,904 | $7.8 | $92,851 |
| 2026-05-21 | Dambkowski Carl | +38,689 | $6.84 | $264,633 |
| 2026-05-18 | Agarwal Arjun | -5,833 | - | - |
| 2026-05-18 | Agarwal Arjun | -2,000 | - | - |
| 2026-05-18 | Agarwal Arjun | -700 | $61.1606 | $42,812 |
| 2026-05-18 | Agarwal Arjun | -800 | $60.3364 | $48,269 |
| 2026-05-18 | Agarwal Arjun | -4,600 | $59.1869 | $272,260 |
| 2026-05-18 | Agarwal Arjun | -4,190 | $58.3449 | $244,465 |
| 2026-05-18 | Agarwal Arjun | +5,833 | $34.39 | $200,597 |
| 2026-05-18 | Agarwal Arjun | +2,000 | $12.5 | $25,000 |
| 2026-05-15 | Goncalves Joana | -3,500 | - | - |
| 2026-05-15 | Goncalves Joana | -3,500 | - | - |
| 2026-05-15 | Goncalves Joana | -100 | $63.52 | $6,352 |
| 2026-05-15 | Goncalves Joana | -2,100 | $62.423 | $131,088 |
| 2026-05-15 | Goncalves Joana | -4,800 | $61.5614 | $295,495 |
| 2026-05-15 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-05-15 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-05-01 | Sandler Laura Lee | -5,000 | - | - |
| 2026-05-01 | Sandler Laura Lee | -100 | $68.48 | $6,848 |
| 2026-05-01 | Sandler Laura Lee | -200 | $67.155 | $13,431 |
| 2026-05-01 | Sandler Laura Lee | -400 | $66.055 | $26,422 |
| 2026-05-01 | Sandler Laura Lee | -300 | $65.1 | $19,530 |
| 2026-05-01 | Sandler Laura Lee | -1,800 | $64.1488 | $115,468 |
| 2026-05-01 | Sandler Laura Lee | -2,200 | $62.5843 | $137,685 |
| 2026-05-01 | Sandler Laura Lee | +5,000 | $7.8 | $39,000 |
| 2026-04-15 | Goncalves Joana | -3,500 | - | - |
| 2026-04-15 | Goncalves Joana | -3,500 | - | - |
| 2026-04-15 | Goncalves Joana | -500 | $67.384 | $33,692 |
| 2026-04-15 | Goncalves Joana | -2,273 | $66.5643 | $151,301 |
| 2026-04-15 | Goncalves Joana | -4,227 | $65.7291 | $277,837 |
| 2026-04-15 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-04-15 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-03-16 | Sandler Laura Lee | -600 | $41.3 | $24,780 |
| 2026-03-16 | Agarwal Arjun | -395 | $41.3 | $16,313 |
| 2026-03-16 | Klein Lawrence Otto | -1,729 | $41.3 | $71,408 |
| 2026-03-16 | Goncalves Joana | -3,500 | - | - |
| 2026-03-16 | Goncalves Joana | -3,500 | - | - |
| 2026-03-16 | Goncalves Joana | -641 | $41.3 | $26,473 |
| 2026-03-16 | Goncalves Joana | -1,177 | $41.9361 | $49,359 |
| 2026-03-16 | Goncalves Joana | -2,902 | $41.2022 | $119,569 |
| 2026-03-16 | Goncalves Joana | -2,921 | $40.1091 | $117,159 |
| 2026-03-16 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-03-16 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-03-16 | Quinlan Paul T | -733 | $41.3 | $30,273 |
| 2026-03-02 | Sandler Laura Lee | -5,000 | - | - |
| 2026-03-02 | Sandler Laura Lee | -2,675 | $33.8077 | $90,436 |
| 2026-03-02 | Sandler Laura Lee | -2,325 | $33.2843 | $77,386 |
| 2026-03-02 | Sandler Laura Lee | +5,000 | $7.8 | $39,000 |
| 2026-02-17 | Goncalves Joana | -3,500 | - | - |
| 2026-02-17 | Goncalves Joana | -3,500 | - | - |
| 2026-02-17 | Goncalves Joana | -936 | $32.7842 | $30,686 |
| 2026-02-17 | Goncalves Joana | -6,064 | $32.3009 | $195,873 |
| 2026-02-17 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-02-17 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-01-23 | Sandler Laura Lee | +130,000 | - | - |
| 2026-01-23 | Sandler Laura Lee | +32,500 | - | - |
| 2026-01-23 | Agarwal Arjun | +70,000 | - | - |
| 2026-01-23 | Agarwal Arjun | +17,500 | - | - |
| 2026-01-23 | Dambkowski Carl | +116,483 | - | - |
| 2026-01-23 | Klein Lawrence Otto | +306,700 | - | - |
| 2026-01-23 | Klein Lawrence Otto | +76,700 | - | - |
| 2026-01-23 | Goncalves Joana | +130,000 | - | - |
| 2026-01-23 | Goncalves Joana | +32,500 | - | - |
| 2026-01-23 | Quinlan Paul T | +130,000 | - | - |
| 2026-01-23 | Quinlan Paul T | +32,500 | - | - |
| 2026-01-15 | Goncalves Joana | -3,500 | - | - |
| 2026-01-15 | Goncalves Joana | -3,500 | - | - |
| 2026-01-15 | Goncalves Joana | -2,619 | $32.237 | $84,429 |
| 2026-01-15 | Goncalves Joana | -4,381 | $31.5626 | $138,276 |
| 2026-01-15 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2026-01-15 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2026-01-02 | Sandler Laura Lee | -5,000 | - | - |
| 2026-01-02 | Sandler Laura Lee | -1,108 | $29.7536 | $32,967 |
| 2026-01-02 | Sandler Laura Lee | -3,144 | $29.0814 | $91,432 |
| 2026-01-02 | Sandler Laura Lee | -8,748 | $28.166 | $246,396 |
| 2026-01-02 | Sandler Laura Lee | +5,000 | $7.8 | $39,000 |
| 2025-12-19 | Goncalves Joana | -3,500 | - | - |
| 2025-12-19 | Goncalves Joana | -3,500 | - | - |
| 2025-12-19 | Goncalves Joana | -3,080 | $31.579 | $97,263 |
| 2025-12-19 | Goncalves Joana | -1,492 | $30.7011 | $45,806 |
| 2025-12-19 | Goncalves Joana | -1,787 | $29.622 | $52,935 |
| 2025-12-19 | Goncalves Joana | -641 | $28.5322 | $18,289 |
| 2025-12-19 | Goncalves Joana | +3,500 | $7.8 | $27,300 |
| 2025-12-19 | Goncalves Joana | +3,500 | $6.84 | $23,940 |
| 2025-12-11 | Martin Christopher Nathan | +35,000 | - | - |