About Stoke Therapeutics Inc
- Industry: Biotechnology
- Exchange: NASDAQ NMS - GLOBAL MARKET
- Country: US
- Website: https://www.stoketherapeutics.com/
Frequently Asked Questions
What is the 52-week range for STOK?
The 52-week high is $40.22 and the 52-week low is $20.32.
What is the P/E ratio for STOK?
The P/E ratio data is currently unavailable.
What is the dividend yield for STOK?
This company does not currently pay a dividend or the data is unavailable.
What is the Return on Equity (ROE)?
The trailing twelve months (TTM) Return on Equity is -59.36%.
What is the Net Profit Margin?
The Net Profit Margin (TTM) is -753.60%.
What is the Price to Book (P/B) Ratio?
The annual Price to Book ratio stands at 5.14.
Analyst Recommendation Trends
Wall Street analyst consensus for STOK over the last few months:
Latest STOK News
Stoke Therapeutics Appoints Bo Cumbo to its Board of Directors, Enhancing Commercial Expertise as the Company Advances Zorevunersen Development Toward Potential FDA Approval and Commercialization
BEDFORD, Mass., September 23, 2026--Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine and has a lead investigational medicine, zorevunersen, in development as a first-in-class potential disease-modifying treatment for Dravet syndrome. Today, the Company announced the appointment of Bo Cumbo to its Board of Directors. Concurrent with Mr. Cumbo’s appointment, Edward Kaye, M.D., has retir
Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)
BEDFORD, Mass., September 16, 2026--Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine and has a lead investigational medicine, zorevunersen, in development as a first-in-class potential disease-modifying treatment for Dravet syndrome. The Company today announced that, effective on September 15, 2026, it granted stock options to purchase an aggregate of 53,175 shares of common stock to
Stoke, Biogen Report Lasting Seizure Reductions In Dravet Syndrome Study
Stoke Therapeutics, Inc. (NASDAQ:STOK), a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine, and Biogen Inc. (NASDAQ:BIIB) today announced presentations
Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16th European Epilepsy Congress (EEC)
–4-year data from the Phase 1/2a open-label extension (OLE) studies showed substantial and durable reductions in seizures and continuing improvements in cognition and behavior in patients treated with zorevunersen on top of standard of care anti-seizure medicines– –New data showed substantial reductions in the most severe seizure types, the leading risk factor for sudden unexpected death in epilepsy (SUDEP)– –Improvements in quality of life were demonstrated through 28 months of treatment– –Zore
Related Stocks (Peers)
Recent Insider Transactions
| Date | Name | Shares Changed | Price | Value |
|---|---|---|---|---|
| 2026-09-23 | Cumbo Alexander | +39,674 | - | - |
| 2026-09-01 | Ticho Barry | -1,600 | $31.0569 | $49,691 |
| 2026-09-01 | Ticho Barry | -3,945 | $30.512 | $120,370 |
| 2026-08-18 | Allan Jonathan | -145 | $32.4681 | $4,708 |
| 2026-08-18 | Allan Jonathan | -2,716 | $32.0072 | $86,932 |
| 2026-08-18 | Ticho Barry | -242 | $32.4681 | $7,857 |
| 2026-08-18 | Ticho Barry | -4,525 | $32.0072 | $144,833 |
| 2026-08-18 | Kaye Edward M. MD | -637 | $32.4681 | $20,682 |
| 2026-08-18 | Kaye Edward M. MD | -11,930 | $32.0072 | $381,846 |
| 2026-08-14 | Allan Jonathan | -6,000 | - | - |
| 2026-08-14 | Allan Jonathan | +6,000 | - | - |
| 2026-08-14 | Ticho Barry | -10,000 | - | - |
| 2026-08-14 | Ticho Barry | +10,000 | - | - |
| 2026-08-14 | Kaye Edward M. MD | -26,250 | - | - |
| 2026-08-14 | Kaye Edward M. MD | +26,250 | - | - |
| 2026-08-03 | Ticho Barry | -1,269 | $29.4539 | $37,377 |
| 2026-08-03 | Ticho Barry | -5,907 | $28.9501 | $171,008 |
| 2026-07-16 | Harrison Seth Loring | +17,786 | - | - |
| 2026-07-16 | Harrison Seth Loring | -17,786 | - | - |
| 2026-07-16 | Harrison Seth Loring | +29,747 | - | - |
| 2026-07-16 | Harrison Seth Loring | -29,747 | - | - |
| 2026-07-16 | Harrison Seth Loring | +7,639 | - | - |
| 2026-07-16 | Harrison Seth Loring | -7,639 | - | - |
| 2026-07-16 | Harrison Seth Loring | +19,441 | - | - |
| 2026-07-16 | Harrison Seth Loring | -19,441 | - | - |
| 2026-07-16 | Harrison Seth Loring | +21,000 | - | - |
| 2026-07-16 | Harrison Seth Loring | -21,000 | - | - |
| 2026-07-16 | Harrison Seth Loring | +11,650 | - | - |
| 2026-07-16 | Harrison Seth Loring | -11,650 | - | - |
| 2026-07-16 | Harrison Seth Loring | +14,777 | - | - |
| 2026-07-16 | Harrison Seth Loring | -14,777 | - | - |
| 2026-07-16 | Harrison Seth Loring | +29,555 | - | - |
| 2026-07-16 | Harrison Seth Loring | -29,555 | - | - |
| 2026-07-15 | McCauley Thomas | +225,000 | - | - |
| 2026-07-01 | Ticho Barry | -500 | $33.2678 | $16,634 |
| 2026-07-01 | Ticho Barry | -6,728 | $32.615 | $219,434 |
| 2026-06-16 | Allan Jonathan | -1,457 | $29.95 | $43,637 |
| 2026-06-03 | Krainer Adrian R. | +17,786 | - | - |
| 2026-06-03 | Burstein Jennifer | +17,786 | - | - |
| 2026-06-03 | TZIANABOS ARTHUR | +17,786 | - | - |
| 2026-06-03 | Smith Julie | +17,786 | - | - |
| 2026-06-03 | Kaye Edward M. MD | +17,786 | - | - |
| 2026-06-03 | Harrison Seth Loring | +17,786 | - | - |
| 2026-06-03 | LEVIN ARTHUR A | +17,786 | - | - |
| 2026-06-01 | Ticho Barry | -1,795 | $30.58 | $54,891 |
| 2026-05-01 | Ticho Barry | -2,243 | $32.79 | $73,548 |
| 2026-04-03 | Kahn Clare | +30,782 | - | - |
| 2026-04-01 | Ticho Barry | -1,838 | $32.66 | $60,029 |
| 2026-03-20 | Allan Jonathan | -601 | $34.4079 | $20,679 |
| 2026-03-20 | Allan Jonathan | -8,692 | $33.6354 | $292,359 |
| 2026-03-19 | Ticho Barry | -1,365 | - | - |
| 2026-03-19 | Ticho Barry | -1,461 | $29.99 | $43,815 |
| 2026-03-19 | Ticho Barry | +1,365 | $2.19 | $2,989 |
| 2026-03-18 | Allan Jonathan | -72 | $32.85 | $2,365 |
| 2026-03-18 | Allan Jonathan | -334 | $31.7888 | $10,617 |
| 2026-03-18 | Allan Jonathan | -4,222 | $31.2838 | $132,080 |
| 2026-03-18 | Ticho Barry | -103 | $32.85 | $3,384 |
| 2026-03-18 | Ticho Barry | -483 | $31.7888 | $15,354 |
| 2026-03-18 | Ticho Barry | -6,100 | $31.2838 | $190,831 |
| 2026-03-18 | Leggett Thomas | -37 | $32.85 | $1,215 |
| 2026-03-18 | Leggett Thomas | -172 | $31.7888 | $5,468 |
| 2026-03-18 | Leggett Thomas | -2,173 | $31.2838 | $67,980 |
| 2026-03-18 | Hoitt Jason | -30 | $32.85 | $986 |
| 2026-03-18 | Hoitt Jason | -139 | $31.7888 | $4,419 |
| 2026-03-18 | Hoitt Jason | -1,762 | $31.2838 | $55,122 |
| 2026-03-17 | Allan Jonathan | -1,791 | $33.3754 | $59,775 |
| 2026-03-17 | Allan Jonathan | -2,476 | $32.7394 | $81,063 |
| 2026-03-17 | Ticho Barry | -2,587 | $33.3754 | $86,342 |
| 2026-03-17 | Ticho Barry | -3,577 | $32.7394 | $117,109 |
| 2026-03-17 | Leggett Thomas | -922 | $33.3754 | $30,772 |
| 2026-03-17 | Leggett Thomas | -1,274 | $32.7394 | $41,710 |
| 2026-03-17 | Hoitt Jason | -748 | $33.3754 | $24,965 |
| 2026-03-17 | Hoitt Jason | -1,033 | $32.7394 | $33,820 |
| 2026-03-15 | Allan Jonathan | -12,000 | - | - |
| 2026-03-15 | Allan Jonathan | -6,000 | - | - |
| 2026-03-15 | Allan Jonathan | -7,475 | - | - |
| 2026-03-15 | Allan Jonathan | +12,000 | - | - |
| 2026-03-15 | Allan Jonathan | +6,000 | - | - |
| 2026-03-15 | Allan Jonathan | +7,475 | - | - |
| 2026-03-15 | Ticho Barry | -10,750 | - | - |
| 2026-03-15 | Ticho Barry | -10,000 | - | - |
| 2026-03-15 | Ticho Barry | -13,100 | - | - |
| 2026-03-15 | Ticho Barry | +10,750 | - | - |
| 2026-03-15 | Ticho Barry | +10,000 | - | - |
| 2026-03-15 | Ticho Barry | +13,100 | - | - |
| 2026-03-15 | Leggett Thomas | -14,750 | - | - |
| 2026-03-15 | Leggett Thomas | +14,750 | - | - |
| 2026-03-15 | Hoitt Jason | -10,000 | - | - |
| 2026-03-15 | Hoitt Jason | +10,000 | - | - |
| 2026-03-15 | Kaye Edward M. MD | -26,250 | - | - |
| 2026-03-15 | Kaye Edward M. MD | -35,500 | - | - |
| 2026-03-15 | Kaye Edward M. MD | +26,250 | - | - |
| 2026-03-15 | Kaye Edward M. MD | +35,500 | - | - |
| 2026-03-13 | LEVIN ARTHUR A | -605 | $36.8 | $22,264 |
| 2026-03-10 | Krainer Adrian R. | -33,243 | $39.7366 | $1,320,964 |
| 2026-03-10 | TZIANABOS ARTHUR | -3,955 | - | - |
| 2026-03-10 | TZIANABOS ARTHUR | -4,355 | $40.0033 | $174,214 |
| 2026-03-10 | TZIANABOS ARTHUR | +3,955 | $8.33 | $32,945 |
| 2026-03-02 | Krainer Adrian R. | -7,229 | $39.6618 | $286,715 |
| 2026-02-17 | Allan Jonathan | +35,000 | - | - |
| 2026-02-17 | Allan Jonathan | +53,000 | - | - |
| 2026-02-17 | Ticho Barry | +40,000 | - | - |
| 2026-02-17 | Ticho Barry | +60,000 | - | - |
| 2026-02-17 | Leggett Thomas | +40,000 | - | - |
| 2026-02-17 | Leggett Thomas | +60,000 | - | - |
| 2026-02-17 | Hoitt Jason | +48,000 | - | - |
| 2026-02-17 | Hoitt Jason | +72,000 | - | - |
| 2026-02-17 | SMITH IAN F | +129,000 | - | - |
| 2026-02-17 | SMITH IAN F | +193,000 | - | - |
| 2025-12-31 | LEVIN ARTHUR A | -1,211 | - | - |
| 2025-12-31 | LEVIN ARTHUR A | +1,211 | - | - |
| 2025-12-08 | Allan Jonathan | -2,678 | $32.6128 | $87,337 |
| 2025-12-08 | Allan Jonathan | -1,300 | $31.5956 | $41,074 |
| 2025-12-08 | Kaye Edward M. MD | -1,331 | $33.1041 | $44,062 |
| 2025-12-08 | Kaye Edward M. MD | -8,274 | $32.52 | $269,070 |
| 2025-12-08 | Kaye Edward M. MD | -3,825 | $31.4387 | $120,253 |
| 2025-12-05 | Allan Jonathan | -2,344 | $31.7597 | $74,445 |
| 2025-12-05 | Allan Jonathan | -5,437 | $31.0828 | $168,997 |
| 2025-12-05 | Allan Jonathan | -1,004 | $31.3304 | $31,456 |
| 2025-12-05 | Ticho Barry | -1,989 | $31.3453 | $62,346 |
| 2025-12-05 | Ticho Barry | -1,673 | $31.3304 | $52,416 |
| 2025-12-05 | Kaye Edward M. MD | -500 | $31.846 | $15,923 |
| 2025-12-05 | Kaye Edward M. MD | -1,681 | $31.1468 | $52,358 |
| 2025-12-05 | Kaye Edward M. MD | -6,367 | $31.3304 | $199,481 |
| 2025-12-04 | Allan Jonathan | -194 | $31.3164 | $6,075 |
| 2025-12-04 | Allan Jonathan | -824 | $30.7635 | $25,349 |
| 2025-12-04 | Ticho Barry | -323 | $31.3164 | $10,115 |
| 2025-12-04 | Ticho Barry | -1,373 | $30.7635 | $42,238 |
| 2025-12-04 | Kaye Edward M. MD | -1,231 | $31.3164 | $38,550 |
| 2025-12-04 | Kaye Edward M. MD | -5,222 | $30.7635 | $160,647 |
| 2025-12-03 | Allan Jonathan | -1,394 | $30.8477 | $43,002 |
| 2025-12-03 | Allan Jonathan | -898 | $30.338 | $27,244 |
| 2025-12-03 | Ticho Barry | -1,225 | $30.8477 | $37,788 |
| 2025-12-03 | Ticho Barry | -789 | $30.338 | $23,937 |
| 2025-12-03 | Kaye Edward M. MD | -651 | $30.8477 | $20,082 |
| 2025-12-03 | Kaye Edward M. MD | -419 | $30.338 | $12,712 |
| 2025-12-03 | Allan Jonathan | -6,000 | - | - |
| 2025-12-03 | Allan Jonathan | +6,000 | - | - |
| 2025-12-03 | Ticho Barry | -10,000 | - | - |
| 2025-12-03 | Ticho Barry | +10,000 | - | - |
| 2025-12-03 | Kaye Edward M. MD | -26,250 | - | - |
| 2025-12-03 | Kaye Edward M. MD | +26,250 | - | - |
| 2025-12-02 | Allan Jonathan | -868 | $30.1419 | $26,163 |
| 2025-12-02 | Allan Jonathan | -1,416 | $29.562 | $41,860 |
| 2025-12-02 | Ticho Barry | -762 | $30.1419 | $22,968 |
| 2025-12-02 | Ticho Barry | -1,244 | $29.562 | $36,775 |
| 2025-12-02 | Kaye Edward M. MD | -405 | $30.1419 | $12,207 |
| 2025-12-02 | Kaye Edward M. MD | -661 | $29.562 | $19,540 |
| 2025-12-01 | Allan Jonathan | -12,357 | - | - |
| 2025-12-01 | Allan Jonathan | +12,357 | - | - |
| 2025-12-01 | Ticho Barry | -11,981 | - | - |
| 2025-12-01 | Ticho Barry | +11,981 | - | - |
| 2025-12-01 | Kaye Edward M. MD | -4,317 | - | - |
| 2025-11-24 | Krainer Adrian R. | -40,472 | $29.7173 | $1,202,719 |
| 2025-11-14 | Krainer Adrian R. | -20,682 | $27.3361 | $565,365 |
| 2025-11-14 | Krainer Adrian R. | -19,790 | $26.6141 | $526,693 |
| 2025-11-03 | Ticho Barry | -100 | $29.35 | $2,935 |
| 2025-11-03 | Ticho Barry | -600 | $27.54 | $16,524 |
| 2025-11-03 | Ticho Barry | -1,455 | $26.0206 | $37,860 |
| 2025-11-03 | Ticho Barry | -3,776 | $25.2242 | $95,247 |
| 2025-10-08 | SMITH IAN F | +380,000 | - | - |
| 2025-10-08 | SMITH IAN F | +570,000 | - | - |
| 2025-10-08 | Kaye Edward M. MD | -25,000 | - | - |
| 2025-10-08 | Kaye Edward M. MD | -25,000 | $30 | $750,000 |
| 2025-10-08 | Kaye Edward M. MD | +25,000 | $0.6 | $15,000 |
| 2025-10-03 | Allan Jonathan | -10,000 | - | - |
| 2025-10-03 | Allan Jonathan | -10,000 | $25.065 | $250,650 |
| 2025-10-03 | Allan Jonathan | +10,000 | $9.15 | $91,500 |
| 2025-10-03 | Kaye Edward M. MD | -42,461 | $25.0867 | $1,065,206 |