About Spero Therapeutics Inc
- Industry: Biotechnology
- Exchange: NASDAQ NMS - GLOBAL MARKET
- Country: US
- Website: https://sperotherapeutics.com/
Frequently Asked Questions
What is the 52-week range for SPRO?
The 52-week high is $3.08 and the 52-week low is $1.08.
What is the P/E ratio for SPRO?
The Price to Earnings (P/E) ratio is 9.39.
What is the dividend yield for SPRO?
This company does not currently pay a dividend or the data is unavailable.
What is the Return on Equity (ROE)?
The trailing twelve months (TTM) Return on Equity is 16.17%.
What is the Net Profit Margin?
The Net Profit Margin (TTM) is 24.90%.
What is the Price to Book (P/B) Ratio?
The annual Price to Book ratio stands at 2.22.
Analyst Recommendation Trends
Wall Street analyst consensus for SPRO over the last few months:
Latest SPRO News
Spero Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
CAMBRIDGE, Mass., Oct. 02, 2026 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a clinical-stage biopharmaceutical company focused on advancing next-generation medicines in immunology and inflammation, today announced that the Compensation Committee of Spero’s Board of Directors approved grants, made on October 1, 2026, of an aggregate of 233,000 restricted stock unit awards (RSUs) and 323,000 stock options to new employees under the Spero Therapeutics, Inc. 2019 Inducement Equity I
Gapping stocks in Tuesday's session
The market is buzzing with gapping stocks on Tuesday. Let's uncover which stocks are experiencing notable gaps during today's session.
Meta Platforms To $650? Here Are 10 Top Analyst Forecasts For Monday
Analysts raised price targets for Meta, IREN, Coinbase, Roblox and others; IREN and Coinbase were upgraded, while other ratings held steady.
HC Wainwright & Co. Maintains Buy on Spero Therapeutics, Raises Price Target to $6
HC Wainwright & Co. analyst Raghuram Selvaraju maintains Spero Therapeutics (NASDAQ:SPRO) with a Buy and raises the price target from $5 to $6.
Related Stocks (Peers)
Recent Insider Transactions
| Date | Name | Shares Changed | Price | Value |
|---|---|---|---|---|
| 2026-08-03 | Zack Debra | +324,675 | - | - |
| 2026-08-03 | Zack Debra | +162,311 | - | - |
| 2026-06-23 | Tregoning Kathleen | +20,000 | - | - |
| 2026-06-23 | Tregoning Kathleen | +10,000 | - | - |
| 2026-06-23 | Smith Cynthia | +20,000 | - | - |
| 2026-06-23 | Smith Cynthia | +10,000 | - | - |
| 2026-06-23 | Jackson Scott Thomas | +20,000 | - | - |
| 2026-06-23 | Jackson Scott Thomas | +10,000 | - | - |
| 2026-06-23 | VINK PATRICK V.J.J. | +20,000 | - | - |
| 2026-06-23 | VINK PATRICK V.J.J. | +10,000 | - | - |
| 2026-06-23 | Deshpande Milind | +20,000 | - | - |
| 2026-06-23 | Deshpande Milind | +10,000 | - | - |
| 2026-06-23 | Pottage John C Jr | +20,000 | - | - |
| 2026-06-23 | Pottage John C Jr | +10,000 | - | - |
| 2026-06-23 | THOMAS FRANK E | +20,000 | - | - |
| 2026-06-23 | THOMAS FRANK E | +10,000 | - | - |
| 2026-05-04 | Rajavelu Esther | -25,240 | $2.51 | $63,352 |
| 2026-02-06 | Rajavelu Esther | -50,816 | $2.36 | $119,926 |
| 2026-02-06 | Rajavelu Esther | -37,101 | $2.36 | $87,558 |
| 2026-02-06 | Keutzer Timothy | -18,652 | $2.36 | $44,019 |
| 2026-02-04 | Keutzer Timothy | -3,471 | $2.24 | $7,775 |
| 2026-02-03 | Keutzer Timothy | -24,224 | $2.14 | $51,839 |
| 2026-02-02 | Keutzer Timothy | +137,000 | - | - |
| 2026-02-02 | Keutzer Timothy | -18,891 | $2.2 | $41,560 |
| 2026-02-02 | Keutzer Timothy | +68,000 | - | - |
| 2026-02-02 | Rajavelu Esther | +498,000 | - | - |
| 2026-02-02 | Rajavelu Esther | -18,442 | $2.2 | $40,572 |
| 2026-02-02 | Rajavelu Esther | +249,000 | - | - |
| 2025-11-07 | Rajavelu Esther | -40,270 | $2.37 | $95,440 |