About Karyopharm Therapeutics Inc
- Industry: Biotechnology
- Exchange: NASDAQ NMS - GLOBAL MARKET
- Country: US
- Website: https://karyopharm.com/
Frequently Asked Questions
What is the 52-week range for KPTI?
The 52-week high is $10.99 and the 52-week low is $0.7471.
What is the P/E ratio for KPTI?
The P/E ratio data is currently unavailable.
What is the dividend yield for KPTI?
This company does not currently pay a dividend or the data is unavailable.
What is the Return on Equity (ROE)?
The trailing twelve months (TTM) Return on Equity is -182.43%.
What is the Net Profit Margin?
The Net Profit Margin (TTM) is -153.28%.
What is the Price to Book (P/B) Ratio?
The annual Price to Book ratio stands at 22.52.
Analyst Recommendation Trends
Wall Street analyst consensus for KPTI over the last few months:
Latest KPTI News
Karyopharm Therapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)
Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted 333 restricted stock units (RSUs) to one newly-hired employee. This RSU award was granted as of September 30, 2026 (the "Grant Date") pursuant to the Company's 2022 Inducement Stock Incentive Plan, as amended, as an inducement material to the new employee entering into employment with Karyopharm in accordance with Nasdaq Listing Rule 5
Let's have a look at the top gainers and losers in the middle of the day of today's session.
Let's have a look at what is happening on the US markets in the middle of the day on Friday. Below you can find the top gainers and losers in today's session.
Traders are paying attention to the gapping stocks in Friday's session.
There are notable gap-ups and gap-downs in today's session. Let's take a look at which stocks are gapping on Friday.
Which stocks are moving before the opening bell on Friday?
Before the US market kicks off on Friday, let's examine the pre-market session and unveil the notable performers among the top gainers and losers.
Karyopharm pushes off debt payment; Amgen eyes broader Imdelltra use
Karyopharm bought an extra month to negotiate with creditors or pursue a deal. Elsewhere, BridgeBio Pharma’s oncology spinout shook up its development plans and a brain-focused gene therapy startup banked $275 million.
12 Health Care Stocks Moving In Friday's Pre-Market Session
Gainers Tenon Medical (NASDAQ:TNON) shares moved upwards by 49.2% to $7.91 during Friday's pre-market session. The company's market cap stands at $3.5 million. Biodexa Pharmaceuticals (NASDAQ:BDRX) stock rose
Karyopharm Therapeutics Signs Forbearance Agreement, Limited Waiver To Indentures For Additional Time To Advance Its Myelofibrosis Program; Did Not Pay $15.8M Due Under Sept. 10 Credit Agreement
https://www.sec.gov/ix?doc=/Archives/edgar/data/1503802/000119312526388621/d94769d8k.htm
Selinexor Sales Forecast and Market Size Analysis to 2034 | Selinexor Market Poised for Growth as Phase III Myelofibrosis Results Open New Commercial Opportunities
Dublin, Sept. 10, 2026 (GLOBE NEWSWIRE) -- The "Selinexor Sales Forecast, and Market Size Analysis - 2034" has been added to ResearchAndMarkets.com's offering. The report provides a comprehensive assessment of the selinexor market across the seven major markets (7MM): the United States, Germany, France, Italy, Spain, the United Kingdom, and Japan. The analysis covers selinexor's approved indications, including multiple myeloma and relapsed or refractory diffuse large B-cell lymphoma (DLBCL), alo
Karyopharm Therapeutics (KPTI) Stock Fair Value Falls After Split Analyst Views On Trial Updates
Price targets on Karyopharm Therapeutics have swung sharply, with one bullish firm trimming its view from US$14 to US$11 and a more cautious house cutting from US$15 to US$3. These shifts reflect the split in analyst commentary, which now hinges on how investors weigh the myelofibrosis opportunity against the endometrial cancer setback and recent stock volatility. Read on to see how to follow this evolving narrative and what to watch as new data and regulatory decisions come through. Stay...
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Recent Insider Transactions
| Date | Name | Shares Changed | Price | Value |
|---|---|---|---|---|
| 2026-10-01 | Abate Kristin | -378 | $1.19 | $450 |
| 2026-09-01 | Abate Kristin | -19 | $2.02 | $38 |
| 2026-07-28 | Poulton Stuart | -189 | $7.1 | $1,342 |
| 2026-05-21 | Su Zhen | +15,508 | - | - |
| 2026-05-21 | Oliger Christy J. | +15,508 | - | - |
| 2026-05-21 | Schor Chen | +15,508 | - | - |
| 2026-05-21 | Greene Barry E | +15,508 | - | - |
| 2026-05-21 | PAKIANATHAN DEEPIKA | +15,508 | - | - |
| 2026-05-21 | BOHLIN GAREN G | +15,508 | - | - |
| 2026-05-14 | Poulton Stuart | -403 | $9.5 | $3,829 |
| 2026-05-14 | Rangwala Reshma | -408 | $9.5 | $3,876 |
| 2026-05-14 | Cheng Sohanya Roshan | -324 | $9.5 | $3,078 |
| 2026-05-14 | Abate Kristin | -53 | $9.5 | $504 |
| 2026-05-14 | Paulson Richard A. | -2,203 | $9.5 | $20,929 |
| 2026-05-14 | Mano Michael | -266 | $9.5 | $2,527 |
| 2026-05-13 | Poulton Stuart | +896 | - | - |
| 2026-05-13 | Rangwala Reshma | +947 | - | - |
| 2026-05-13 | Cheng Sohanya Roshan | +947 | - | - |
| 2026-05-13 | Abate Kristin | +121 | - | - |
| 2026-05-13 | Paulson Richard A. | +4,920 | - | - |
| 2026-05-13 | Mano Michael | +700 | - | - |
| 2026-04-21 | Rangwala Reshma | -449 | $8.94 | $4,014 |
| 2026-03-02 | Abate Kristin | -559 | $9.4095 | $5,260 |
| 2026-03-02 | Poulton Stuart | -5,101 | $9.4095 | $47,998 |
| 2026-03-02 | Cheng Sohanya Roshan | -4,604 | $9.4095 | $43,321 |
| 2026-03-02 | Mano Michael | -3,526 | $9.4095 | $33,178 |
| 2026-03-02 | Paulson Richard A. | -12,361 | $9.4095 | $116,311 |
| 2026-03-02 | Rangwala Reshma | -5,066 | $9.4095 | $47,669 |
| 2026-02-17 | Poulton Stuart | -378 | $8.63 | $3,262 |
| 2026-02-05 | Paulson Richard A. | +81,060 | - | - |
| 2026-02-03 | Macomber Lori | -1,626 | $6.3 | $10,244 |
| 2026-01-31 | Cheng Sohanya Roshan | +32,415 | - | - |
| 2026-01-31 | Rangwala Reshma | +32,415 | - | - |
| 2026-01-31 | Macomber Lori | +32,415 | - | - |
| 2026-01-31 | Mano Michael | +32,415 | - | - |
| 2026-01-31 | Poulton Stuart | +32,415 | - | - |
| 2026-01-28 | Abate Kristin | -50 | $7.03 | $352 |
| 2026-01-27 | Abate Kristin | +92 | - | - |
| 2026-01-21 | Abate Kristin | -265 | $5.96 | $1,579 |
| 2025-10-15 | Abate Kristin | +12,799 | - | - |
| 2025-10-15 | Poulton Stuart | +39,682 | - | - |
| 2025-10-15 | Mano Michael | +43,650 | - | - |
| 2025-10-15 | Paulson Richard A. | +114,285 | - | - |
| 2025-10-15 | Cheng Sohanya Roshan | +43,650 | - | - |
| 2025-10-15 | Macomber Lori | +43,650 | - | - |