$43.54-0.46|(-1.05%)
52W H: 86.7452W L: 43.0065Beta: 0.38

About Ionis Pharmaceuticals Inc

Frequently Asked Questions

What is the 52-week range for IONS?

The 52-week high is $86.74 and the 52-week low is $43.0065.

What is the P/E ratio for IONS?

The P/E ratio data is currently unavailable.

What is the dividend yield for IONS?

This company does not currently pay a dividend or the data is unavailable.

What is the Return on Equity (ROE)?

The trailing twelve months (TTM) Return on Equity is -110.92%.

What is the Net Profit Margin?

The Net Profit Margin (TTM) is -64.66%.

What is the Price to Book (P/B) Ratio?

The annual Price to Book ratio stands at 26.20.

Analyst Recommendation Trends

Wall Street analyst consensus for IONS over the last few months:

2026-09-01
Buy: 17
S.Buy: 8
Hold: 7
Sell: 0
2026-08-01
Buy: 17
S.Buy: 8
Hold: 6
Sell: 0
2026-07-01
Buy: 16
S.Buy: 11
Hold: 6
Sell: 0
2026-06-01
Buy: 17
S.Buy: 10
Hold: 6
Sell: 0

Latest IONS News

Cathie Wood Makes $64 Million Bet on Two Stocks

The latest trades reveal where Wood sees opportunity

Yahoo9/28/2026

4 RNA Therapeutics Stocks Leading the Next Wave of Innovation

RNA therapeutics are gaining momentum as Alnylam, Ionis, Wave Life Sciences and Arcturus advance innovative treatments targeting a range of diseases.

Yahoo9/28/2026

Alnylam Pharmaceuticals: More Than Meets The Eye After CARDIO-TTRansform

Alnylam Pharmaceuticals, Inc. is down on ATTR-CM fears. TRITON-CM could still succeed, downside is buffered, and shares look undervalued. Click for an ALNY update.

SeekingAlpha9/28/2026

Ionis Pharmaceuticals (IONS) Stock Looks Pricey On Its 45% YTD Slide

Ionis Pharmaceuticals has had a rough run so far this year, even as fresh clinical results have put its drug pipeline in the spotlight. With the share price under pressure, the real issue for investors is how well the current valuation lines up with the sales its business is generating and may be able to support over time. The stock is down about 45.0% year to date. This puts a sharp spotlight on whether today's market value still lines up with what Ionis can justify through its sales...

Yahoo9/25/2026

Failure of Novartis’ Pelacarsen Could Reshape the Lp(a) Race for CRISPR and Ionis

Novartis AG’s (NYSE:NVS) Phase 3 Lp(a)HORIZON setback carries implications beyond the Swiss drugmaker. Pelacarsen significantly lowered lipoprotein(a), or Lp(a), but failed to produce a statistically significant reduction in major cardiovascular events, according to the information provided. READ ALSO: Can a Tagrisso Combination Strengthen AstraZeneca’s Path to $80 Billion? That disconnect matters for companies developing other […]

Yahoo9/24/2026

HC Wainwright & Co. Reiterates Buy on Ionis Pharmaceuticals, Maintains $100 Price Target

HC Wainwright & Co. analyst Mitchell S. Kapoor reiterates Ionis Pharmaceuticals (NASDAQ:IONS) with a Buy and maintains $100 price target.

Benzinga9/24/2026

The Biggest Losers In Biotech — And It Had Nothing To Do With 'Compelling,' 'Best-In-Disease' Data

Biotech stocks widely slumped Wednesday, with Rapport Therapeutics, Climb Bio and Cullinan Therapeutics among some of the hardest-hit names.

Yahoo9/23/2026

Roche, Ionis RNA drug scores in kidney disease study

The results position Roche to bring a new kind of medicine to market for IgA nephropathy, a disease that’s drawn considerable attention of late from drugmakers.

Yahoo9/23/2026

Ionis Delivers Positive Late-Stage Results for Two Partnered Drugs

IONS posts positive phase III results for two partnered drugs, with ulefnersen meeting its ALS endpoint and sefaxersen cutting proteinuria.

Yahoo9/23/2026

Ionis and Roche Advance First RNA-Targeted Therapy for Autoimmune Kidney Disease

Ionis Pharmaceuticals Inc. (NASDAQ:IONS) and licensing partner Roche Holdings AG (OTC:RHHBY) on Wednesday shared prespecified interim outcomes from their ongoing Phase 3 IMAgINATION trial of investigational sefaxersen in adults diagnosed with primary IgA nephropathy (IgAN). "These interim phase 3 results show the clinical potential of sefaxersen to modify a key surrogate endpoint of kidney function in people with IgA nephropathy’’ said Levi Garraway, Roche’s Chief Medical Officer and Head of Glo

Yahoo9/23/2026

Ionis announces positive interim data from partner Roche’s Phase 3 IMAgINATION study in IgA nephropathy (IgAN)

CARLSBAD, Calif., September 23, 2026--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) and partner Roche today announced positive prespecified interim results from the ongoing Phase 3 IMAgINATION study evaluating investigational sefaxersen in adults with primary IgA nephropathy (IgAN). The study met its primary endpoint with sefaxersen achieving statistically significant and clinically meaningful improvements in proteinuria reduction, compared to placebo at 37 weeks, as measured by 24-hour urine prote

Yahoo9/23/2026

Ionis Pharmaceuticals And Partner Roche Said Prespecified Interim Results From Phase 3 IMAgINATION Study Of Sefaxersen For Primary IgA Nephropathy Met Its Primary Endpoint Of Statistically Significant And Clinically Meaningful Improvements In Proteinuria Reduction Vs. Placebo At 37 Weeks

– Sefaxersen demonstrated statistically significant and clinically meaningful reductions in proteinuria versus placebo at 37 weeks, showing best-in-class potential –– IgAN is a progressive kidney disease that is

Benzinga9/23/2026

Ionis to Seek Expedited FDA Review for ALS Drug

Ionis Pharmaceuticals and Otsuka Pharmaceutical report positive Phase 3 data for ulefnersen, an investigational RNA-targeted drug for ALS.

Benzinga9/22/2026

Ionis announces positive topline results from Phase 3 FUSION study of ulefnersen marking significant milestone in advancing first potential disease modifying treatment for FUS-ALS

CARLSBAD, Calif., September 22, 2026--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) and Otsuka Pharmaceutical Development & Commercialization, Inc., today announced positive topline results from the Phase 3 FUSION trial evaluating ulefnersen, an investigational RNA-targeted medicine, in people living with amyotrophic lateral sclerosis (ALS) caused by mutations in the fused in sarcoma (FUS) gene, also known as FUS-ALS. The study met its primary endpoint, with ulefnersen demonstrating a statistically

Yahoo9/22/2026

Beyond Meta, Cathie Wood’s ARKG Loads Up On These 4 Biotech Names

ARK’s latest portfolio moves spotlighted IONS, VCYT, SCTX, and BEAM as the firm increased its biotech exposure alongside a major Meta purchase.

Yahoo9/22/2026

Cathie Wood Loads Up On Biotech: 5 ETFs Holding Her Latest Bets

Cathie Wood’s ARKG bought Ionis, Beam, Veracyte and Scribe Therapeutics. Here are the biotech ETFs that also hold her latest bets.

Benzinga9/22/2026

JP Morgan Maintains Overweight on Ionis Pharmaceuticals, Lowers Price Target to $70

JP Morgan analyst Jessica Fye maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Overweight and lowers the price target from $76 to $70.

Benzinga9/22/2026

Cathie Wood Makes a Big AI Bet and Cuts Bitcoin Exposure

Ark Invest added nearly $25 million of CoreWeave as it trimmed several major AI and technology holdings

Yahoo9/21/2026

NVS Gets Positive CHMP Opinion for Cosentyx for Another Indication

NVS' Cosentyx wins a positive EU opinion for PMR, backed by late-stage data, potentially expanding its use beyond existing inflammatory conditions.

Yahoo9/21/2026

Investors Dumped Ionis Pharmaceuticals Stock -- But Wall Street Hasn't Budged From Its Bullish Outlook

Shares of Ionis are down more than 40% so far this year.

Yahoo9/20/2026

Ionis Pharmaceuticals Eyes TRYNGOLZA Growth as Pipeline Faces Cardio Setbacks

Ionis Pharmaceuticals (NASDAQ:IONS) CEO Brett Monia outlined recent regulatory wins, commercial-launch progress and several pipeline updates at the Morgan Stanley Global Healthcare Conference, while acknowledging setbacks in late-stage cardiovascular studies. Monia said the company has secured two

Yahoo9/19/2026

Ionis Pharmaceuticals (IONS) Dropped, What Is Behind The Latest Attention?

Ionis Pharmaceuticals (IONS) is back in focus after partner Novartis reported that the pivotal Phase 3 Lp(a)HORIZON trial of pelacarsen failed to reduce major cardiovascular events despite sharply lowering Lp(a) levels. The pelacarsen setback comes after a sharp reset in sentiment. Ionis Pharmaceuticals has posted a 7-day share price return of negative 15.99% and a 30-day share price return of negative 21.59%. Despite this, the company still has a 5-year total shareholder return of 25.67%,...

Yahoo9/18/2026

Can AstraZeneca's Broad Pipeline Offset Recent Setbacks?

AZN's pipeline setbacks weigh on its stock, but a deep late-stage pipeline and 20+ expected readouts offer key catalysts.

Yahoo9/18/2026

Novartis (NVS) and Ionis (IONS)’ Big Cholesterol Bet Comes Up Short in Late-Stage Trial

On September 5, 2026, Reuters reported that pelacarsen, an experimental drug from Novartis AG (NYSE:NVS) and partner Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) meant to lower a cholesterol-carrying particle called Lp(a), failed to reduce heart attacks, strokes and related cardiovascular events in the Lp(a)HORIZON trial, which enrolled more than 8,000 patients. The drug did lower Lp(a) levels […]

Yahoo9/17/2026

Amneal (AMRX) Surges 8.6%: Is This an Indication of Further Gains?

Amneal (AMRX) witnessed a jump in share price last session on above-average trading volume. The latest trend in earnings estimate revisions for the stock doesn't suggest further strength down the road.

Yahoo9/17/2026

Novartis Suffers Another Setback After Two High-Profile Surprises Hammered Shares

Novartis added another failure to its docket Wednesday, dropping an experimental treatment for the muscle-wasting disease.

Yahoo9/16/2026

Ionis Pharmaceuticals, Inc. (IONS) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Ionis Pharmaceuticals, Inc. (IONS) Morgan Stanley 24th Annual Global Healthcare Conference September 16, 2026 7:45 AM EDTCompany ParticipantsBrett Monia -...

SeekingAlpha9/16/2026

Baron Health Care Fund Q2 2026 Portfolio Activity

During the quarter, we added 8 new positions and exited 6 positions, bringing the number of positions in the Fund to 43.

SeekingAlpha9/16/2026

PHVS Stock Rises 10% in a Month: What Is Driving the Rally?

Pharvaris gains as strong phase III data show deucrictibant XR reduces HAE attacks 83%, supporting plans for regulatory submissions in 2027.

Yahoo9/15/2026

Oligonucleotide Therapeutics Market Outlook 2026-2035 - Featuring Profiles of Alnylam Pharmaceuticals, Ionis Pharmaceuticals, and Sarepta Therapeutics

Oligonucleotide Therapeutics Expand Beyond Rare Diseases as RNA Innovation, Targeted Delivery and Patient-Friendly Dosing Accelerate AdoptionDublin, Sept. 15, 2026 (GLOBE NEWSWIRE) -- "Oligonucleotide Therapeutics Market Opportunity, Growth Drivers, Industry Trend Analysis, and Forecast 2026-2035" has been added to ResearchAndMarkets.com's offering. Global Oligonucleotide Therapeutics Market to Reach USD 72.1 Billion by 2035 at a 23.4% CAGR The global oligonucleotide therapeutics market was valu

Yahoo9/15/2026

Guggenheim Maintains Buy on Ionis Pharmaceuticals, Lowers Price Target to $80

Guggenheim analyst Debjit Chattopadhyay maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Buy and lowers the price target from $89 to $80.

Benzinga9/15/2026

Ionis Has Its First Neurology Launch, But Can Zanvastro Justify Its $285,000 Price?

Ionis Pharmaceuticals, Inc. (NASDAQ:IONS) has turned decades of RNA research into its first independently launched neurology medicine. The FDA-approved Zanvastro, chemically known as zilganersen, for adults and children with Alexander disease, has taken the lead as the first approved disease-modifying treatment for the rare neurological disorder. Ionis has set a price of $285,000 per dose […]

Yahoo9/11/2026

BioCryst Pharmaceuticals: Why The Selloff Could Be An Opportunity

BioCryst Pharmaceuticals, Inc. stock update: Orladeyo Q2 revenue rose 6.7%, debt fell, and navenibart adds HAE upside. Click for more on BCRX.

SeekingAlpha9/11/2026

BofA Sees Limited Damage from Novartis (NVS)’ Pelacarsen Miss While Citi Looks Towards Ionis (IONS)

Novartis AG’s (NYSE:NVS) pelacarsen failed an important test. Although the experimental medicine lowered lipoprotein(a), or Lp(a), it did not produce a statistically significant reduction in cardiovascular events in the Phase 3 Lp(a)HORIZON study. Bank of America does not believe the result breaks the Novartis (NYSE:NVS) investment thesis. The firm estimates that the failed study creates […]

Yahoo9/11/2026

Royalty Pharma (RPRX): Can Downside Protection Offset Pelacarsen’s Phase 3 Failure?

Royalty Pharma plc (NASDAQ:RPRX) disclosed that pelacarsen failed the Phase 3 Lp(a)HORIZON cardiovascular-outcomes trial conducted by Novartis AG (NYSE:NVS). The randomized, double-blind study enrolled 8,323 patients with elevated lipoprotein(a), or Lp(a), and established cardiovascular disease. Pelacarsen lowered Lp(a), but the study did not meet its primary endpoint of reducing cardiovascular events compared with placebo in […]

Yahoo9/10/2026

Ionis Pharmaceuticals, Inc. (IONS) Presents at Wells Fargo 21st Annual Healthcare Conference Transcript

Ionis Pharmaceuticals, Inc. (IONS) Wells Fargo 21st Annual Healthcare Conference September 10, 2026 8:45 AM EDTCompany ParticipantsBrett Monia - Founder,...

SeekingAlpha9/10/2026

Cathie Wood Is Loading Up on Ionis Pharmaceuticals (IONS) Stock. Here's the Bet She's Making.

Ionis Pharmaceuticals is promising in multiple ways -- but it's not dirt cheap or without risks.

Yahoo9/9/2026

Novartis' Del-desiran Fails Late-Stage DM1 Study, Shares Fall

NVS' del-desiran fails the HARBOR study's primary endpoint, adding to recent pipeline setbacks as investors await next steps.

Yahoo9/9/2026

Theravance Bio (TBPH) Up 0.8% Since Last Earnings Report: Can It Continue?

Theravance Bio (TBPH) reported earnings 30 days ago. What's next for the stock? We take a look at earnings estimates for some clues.

Yahoo9/9/2026

Barclays Maintains Overweight on Ionis Pharmaceuticals, Lowers Price Target to $85

Barclays analyst Eliana Merle maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Overweight and lowers the price target from $90 to $85.

Benzinga9/9/2026

How Novartis' Double-Stacked Failures Reverberated Through Biopharma

Novartis and Ionis' high-profile Lp(a) flop on Friday reverberated through biotech stocks on Tuesday, leading to a widespread drop.

Yahoo9/8/2026

Novartis Stock Tanks Following Third Major Pipeline Setback

Following two trial misses and a third clinical setback, analysts fear Novartis may miss its 2030 growth targets without further acquisitions.

Yahoo9/8/2026

NVS Stock Clocks Worst Day In Over 20 Years After Second Trial Failure In A Week — DYN, SRPT Slip In Sympathy

The company said on Tuesday that its experimental drug del-desiran failed in a late-stage trial.

Yahoo9/8/2026

Morgan Stanley Maintains Overweight on Ionis Pharmaceuticals, Lowers Price Target to $104

Morgan Stanley analyst Michael Ulz maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Overweight and lowers the price target from $110 to $104.

Benzinga9/8/2026

Amgen: Why Rivals' Cholesterol Drug Fail Is Bad News For The Pharma (Rating Downgrade)

Amgen (AMGN) drops after Novartis’ pelacarsen Phase 3 miss, pressuring olpasiran’s thesis amid patent cliffs. Click here to read my most recent analysis.

SeekingAlpha9/8/2026

Novartis pelacarsen Lp(a) trial fails, raising doubts for Amgen, Lilly

Pelacarsen lowered Lp(a) levels in more than 8,000 patients but did not reduce the risk of heart attacks, strokes, or cardiovascular death

Yahoo9/8/2026

Novartis Stock Drops as Trial Failures Ripple Across Biotech Partners

On Tuesday, Novartis AG (NYSE:NVS) stock witnessed one of the sharpest single-day declines for the company in recent history. Phase 3 HARBOR Trial Misses Primary Endpoint On Tuesday, the company shared data from the global Phase 3 HARBOR study evaluating del-desiran for myotonic dystrophy type 1 (DM1). The study did not demonstrate statistically significant improvement versus placebo on the primary endpoint of video hand opening time (vHOT), a novel measure of hand myotonia. Read Also: A Wall St

Yahoo9/8/2026

Ionis Pharmaceuticals Shares Fall After Pelacarsen Phase 3 Trial Misses Primary Endpoint

Ionis Pharmaceuticals (NASDAQ:IONS) shares fell 13. 1% to $50.

Yahoo9/8/2026

Why Is Eli Lilly Stock Falling Tuesday?

Eli Lilly (LLY) falls 2% amid a broader healthcare sell-off. Key support levels, technical breakdown, and market outlook analyzed.

Benzinga9/8/2026

Goldman Sachs Maintains Neutral on Ionis Pharmaceuticals, Lowers Price Target to $56

Goldman Sachs analyst Salveen Richter maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Neutral and lowers the price target from $69 to $56.

Benzinga9/8/2026

Robinhood To Rally Around 23%? Here Are 10 Top Analyst Forecasts For Tuesday

Analysts raised targets for NOW, HOOD, MSTR, ABNB and CLYM, while cutting APP and IONS; ratings largely remain positive.

Benzinga9/8/2026

BMO Capital Maintains Market Perform on Ionis Pharmaceuticals, Lowers Price Target to $54

BMO Capital analyst David Lebowitz maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Market Perform and lowers the price target from $61 to $54.

Benzinga9/8/2026

Novartis, Ionis Pharmaceuticals And Other Big Stocks Moving Lower In Tuesday’s Pre-Market Session

U.S. stock futures fell as Novartis plunged 12.7% after pelacarsen’s Phase III trial missed its endpoint; other biotech stocks also declined.

Benzinga9/8/2026

Canaccord Genuity Maintains Buy on Ionis Pharmaceuticals, Lowers Price Target to $85

Canaccord Genuity analyst Gary Nachman maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Buy and lowers the price target from $95 to $85.

Benzinga9/8/2026

HC Wainwright & Co. Maintains Buy on Ionis Pharmaceuticals, Lowers Price Target to $100

HC Wainwright & Co. analyst Mitchell S. Kapoor maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Buy and lowers the price target from $115 to $100.

Benzinga9/8/2026

Market-Moving News for September 8th

NVS: -13% | Novartis shares are trading lower after the company announced the pelacarsen phase III Lp(a)HORIZON trial did not meet its primary endpoint. IONS: -13% | Ionis Pharmaceuticals shares are trading lower amid

Benzinga9/8/2026

Ionis Pharmaceuticals, Inc. (IONS) Discusses FDA Approval and Launch Strategy for ZANVASTRO in Alexander Disease - Slideshow

2026-09-07. The following slide deck was published by Ionis Pharmaceuticals, Inc.

SeekingAlpha9/7/2026

Novartis Late-Stage Cardiovascular Outcome Study Fails, Stock Down

Novartis' pelacarsen study failed to cut cardiovascular events, clouding prospects for the drug and highlighting portfolio challenges.

Yahoo9/7/2026

Amgen Shares Fall as Novartis' Pelacarsen Misses Phase III Study Goal

AMGN shares fall as NVS' pelacarsen setback casts investor concern over whether olpasiran can deliver positive phase III outcome data.

Yahoo9/7/2026

Novartis, Ionis drug failure spurs questions about an emerging class of heart medicines

Pelacarsen didn’t protect heart health despite lowering levels of a protein particle, “Lp(a),” in a large clinical trial — a surprise result with important implications for cardiovascular drug research.

Yahoo9/5/2026

NVS, IONS, AMGN Stocks Drop After-Hours — What’s Driving The Selloff?

Novartis said on Friday that its late-stage trial of pelacarsen failed to reduce the risk of cardiovascular events.

Yahoo9/4/2026

Novartis, Ionis Tumble On Surprise Flop For Heart Drug

Novartis said late Friday its Ionis-partnered Lp(a) blocker failed in testing. The results sent Novartis and Ionis stocks tumbling.

Yahoo9/4/2026

Stay updated with the stocks that are on the move in today's after-hours session.

After the closing bell on Friday, let's take a glimpse of the US markets and explore the top gainers and losers in today's after-hours session.

ChartMill9/4/2026

Ionis partner Novartis announces Lp(a)HORIZON Phase 3 topline results for pelacarsen in patients with elevated Lp(a) and established cardiovascular disease (CVD)

CARLSBAD, Calif., September 04, 2026--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) partner Novartis today announced that the pelacarsen Phase 3 Lp(a)HORIZON study, a pioneering cardiovascular outcomes trial, did not meet its primary endpoint of reducing the risk of cardiovascular events, a composite of cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, and urgent coronary revascularization requiring hospitalization, compared to placebo. Consistent with previous studies, subst

Yahoo9/4/2026

Novartis’ Pelacarsen Phase III Lp(a)HORIZON Trial Fails Primary Cardiovascular Endpoint; Lowered Lp(a) Levels But Did Not Reduce CV Events

Novartis today announced that the pelacarsen phase III Lp(a)HORIZON trial, a pioneering cardiovascular outcomes study, did not meet its primary endpoint of reducing the risk of cardiovascular events, a composite of

Benzinga9/4/2026

This Biotech Wins a Big FDA Approval. Why Wall Street Is Shrugging.

Ionis Pharmaceuticals wins regulatory clearance for its quarterly injection, Zanvastro, in Alexander disease. Analysts are focused elsewhere.

Yahoo9/4/2026

Ionis Pharmaceuticals Wins FDA Approval for First Alexander Disease Treatment

Ionis Pharmaceuticals (NASDAQ:IONS) said the U.S. Food and Drug Administration has approved ZANVASTRO as the first and only disease-modifying treatment for Alexander disease, an ultra-rare, progressive neurological disorder caused by pathogenic variants in the GFAP gene. The approval includes a bro

Yahoo9/4/2026

Ionis Pharmaceuticals, Inc. (IONS) Discusses FDA Approval and Launch Strategy for ZANVASTRO in Alexander Disease Transcript

Ionis Pharmaceuticals, Inc. (IONS) Discusses FDA Approval and Launch Strategy for ZANVASTRO in Alexander Disease September 4, 2026 10:00 AM EDTCompany...

SeekingAlpha9/4/2026

IONS Secures FDA Nod for Rare Brain Disorder Drug Zanvastro

Ionis' FDA approval of Zanvastro marks the first disease-modifying treatment for Alexander disease and adds a priority review voucher.

Yahoo9/4/2026

Ionis: Downgrading To Sell After A Series Of Unfortunate Events

Ionis Pharmaceuticals, Inc. faces significant setbacks after initial optimism, with shares dropping sharply from 52-week highs. Read more on IONS stock here.

SeekingAlpha9/4/2026

Ionis Drug Wins FDA Approval as First Alexander Disease Treatment

The U.S. Food and Drug Administration has approved Zanvastro (zilganersen), manufactured by Ionis Pharmaceuticals Inc. (NASDAQ:IONS), for Alexander disease in adult and pediatric patients. Zanvastro becomes the first and only disease-modifying therapy available for this ultra-rare, progressive, and frequently fatal neurological disorder. Prior to this regulatory authorization, clinical care for affected individuals remained strictly limited to symptom management. First Approved Disease-Modifying

Yahoo9/4/2026

Needham Reiterates Buy on Ionis Pharmaceuticals, Maintains $86 Price Target

Needham analyst Joseph Stringer reiterates Ionis Pharmaceuticals (NASDAQ:IONS) with a Buy and maintains $86 price target.

Benzinga9/4/2026

Why Did Ionis Pharmaceuticals (IONS) Stock Drop After Its Latest Update?

Ionis Pharmaceuticals (IONS) just received U.S. FDA approval for ZANVASTRO, an RNA targeted treatment for Alexander disease in pediatric and adult patients. The stock now reflects a new approved rare disease asset. Even with the FDA approval for ZANVASTRO, Ionis Pharmaceuticals shares have been under pressure in the near term, with the 1-day share price return down 5.22% and the 7-day share price return down 6.89%. The 30-day share price return is up 5.56% from a weaker base, and the...

Yahoo9/4/2026

BMO Capital Maintains Market Perform on Ionis Pharmaceuticals, Raises Price Target to $61

BMO Capital analyst David Lebowitz maintains Ionis Pharmaceuticals (NASDAQ:IONS) with a Market Perform and raises the price target from $60 to $61.

Benzinga9/4/2026

Ionis Pharmaceuticals Exec Says Zanvastro Will Be Available At List Price Of $285K Per Dose

https://ir.ionis.com/events/event-details/zanvastrotm-zilganersen-fda-approval-webcas

Benzinga9/4/2026

Ionis’ rare neurology drug approved; Pfizer inks an ADC deal

Zanvastro is now the first approved medicine for Alexander disease. Elsewhere, an immune system specialist posted positive results and a cell therapy developer turned to layoffs.

Yahoo9/4/2026

HC Wainwright & Co. Reiterates Buy on Ionis Pharmaceuticals, Maintains $115 Price Target

HC Wainwright & Co. analyst Mitchell S. Kapoor reiterates Ionis Pharmaceuticals (NASDAQ:IONS) with a Buy and maintains $115 price target.

Benzinga9/4/2026

Ionis Pharmaceuticals (IONS) Gains First-Mover Advantage with FDA Approval of Rare Brain Disease Drug

The U.S. FDA has approved Ionis Pharmaceuticals, Inc. (NASDAQ:IONS)’s Zanvastro (zilganersen) as the first FDA-approved treatment for Alexander disease (AxD), a rare, progressive neurological disorder caused by mutations in the GFAP gene. The disease affects fewer than 1,000 people in the U.S. and can lead to seizures, loss of developmental milestones, impaired movement, and other […]

Yahoo9/4/2026

IONS Edges Up After-Hours On FDA’s Green Light For Neurology Drug After Being Dragged Down By Ultragenyx’s Failed Trial

Zanvastro is now approved for children and adults with Alexander disease, a rare and often fatal brain condition that affects fewer than one in a million people.

Yahoo9/3/2026

FDA Approves Zanvastro For Treatment Of Alexander Disease

https://www.fda.gov/news-events/press-announcements/fda-approves-first-drug-treat-alexander-disease

Benzinga9/3/2026

Ionis to present at upcoming investor conferences

CARLSBAD, Calif., September 03, 2026--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences:

Yahoo9/3/2026

Related Stocks (Peers)

Companies operating in similar sectors to IONS:

Recent Insider Transactions

DateNameShares ChangedPriceValue
2026-08-31Birchler Brian+58$51.306$2,976
2026-08-31O'NEIL PATRICK R.+63$51.306$3,232
2026-08-31Monia Brett P+98$51.306$5,028
2026-08-31BENNETT C FRANK+110$51.306$5,644
2026-07-31Hayden Michael R+5,000$51.6$258,000
2026-07-30Hayden Michael R+15,000$53.38$800,700
2026-07-15Reikes Peter N+3,399--
2026-07-15HANTSON LUDWIG+3,399--
2026-07-15HERMAN JOAN E-5,220--
2026-07-15HERMAN JOAN E+5,220--
2026-07-15BERTHELSEN SPENCER R-5,220--
2026-07-15BERTHELSEN SPENCER R+5,220--
2026-07-07Kordasiewicz Holly B.-362$84.3$30,517
2026-07-07Diaz Allene M.-10,111--
2026-07-07Diaz Allene M.-10,111$85.4156$863,637
2026-07-07Diaz Allene M.+10,111$47.11$476,329
2026-07-07BENNETT C FRANK-15,000--
2026-07-07BENNETT C FRANK-15,000$85.462$1,281,930
2026-07-07BENNETT C FRANK+15,000--
2026-07-07BENNETT C FRANK-5,536$83.579$462,693
2026-07-01Diaz Allene M.+2,301--
2026-07-01Diaz Allene M.+5,369--
2026-07-01YANG MICHAEL J.+2,301--
2026-07-01YANG MICHAEL J.+5,369--
2026-07-01Hayden Michael R+2,301--
2026-07-01Hayden Michael R+5,369--
2026-07-01LOSCALZO JOSEPH+2,301--
2026-07-01LOSCALZO JOSEPH+5,369--
2026-07-01HERMAN JOAN E+2,301--
2026-07-01HERMAN JOAN E+5,369--
2026-07-01KLEIN JOSEPH III+2,301--
2026-07-01KLEIN JOSEPH III+5,369--
2026-07-01KLEIN JOSEPH III-11,518--
2026-07-01KLEIN JOSEPH III-11,419$79.0394$902,551
2026-07-01KLEIN JOSEPH III-99$79.45$7,866
2026-07-01KLEIN JOSEPH III+11,518$39.94$460,029
2026-07-01BERTHELSEN SPENCER R+2,301--
2026-07-01BERTHELSEN SPENCER R+5,369--
2026-06-26Monia Brett P-50,000--
2026-06-26Monia Brett P-50,000$80.59$4,029,500
2026-06-26Monia Brett P+50,000$56.78$2,839,000
2026-06-25Swayze Eric-10,602$79.1824$839,492
2026-06-25Monia Brett P-21,072--
2026-06-25Monia Brett P-21,072$78.49$1,653,941
2026-06-25Monia Brett P+21,072$32.6$686,947
2026-06-24Monia Brett P-14,565--
2026-06-24Monia Brett P-14,565$78.4128$1,142,082
2026-06-24Monia Brett P+14,565$32.6$474,819
2026-06-15BERTHELSEN SPENCER R-8,000--
2026-06-15BERTHELSEN SPENCER R-8,000$73.49$587,920
2026-06-15BERTHELSEN SPENCER R+8,000$24.42$195,360
2026-06-12Kordasiewicz Holly B.-21,000--
2026-06-12Kordasiewicz Holly B.-7,951--
2026-06-12Kordasiewicz Holly B.-19,895--
2026-06-12Kordasiewicz Holly B.-12,000--
2026-06-12Kordasiewicz Holly B.-19,842$74.0503$1,469,306
2026-06-12Kordasiewicz Holly B.-41,004$73.0934$2,997,122
2026-06-12Kordasiewicz Holly B.+19,895$56.78$1,129,638
2026-06-12Kordasiewicz Holly B.+12,000$32.6$391,200
2026-06-12Kordasiewicz Holly B.+21,000$60.89$1,278,690
2026-06-12Kordasiewicz Holly B.+7,951$60.89$484,136
2026-06-04Reikes Peter N+10,753--
2026-06-04HANTSON LUDWIG+10,753--
2026-06-01BERTHELSEN SPENCER R-8,000--
2026-06-01BERTHELSEN SPENCER R-8,000$75.67$605,360
2026-06-01BERTHELSEN SPENCER R+8,000$24.42$195,360
2026-05-14Monia Brett P-3,220--
2026-05-14Monia Brett P-3,220$78.6793$253,347
2026-05-14Monia Brett P+3,220$32.6$104,972
2026-05-13Monia Brett P-1,316--
2026-05-13Monia Brett P-1,316$78.013$102,665
2026-05-13Monia Brett P+1,316$32.6$42,902
2026-05-04LOSCALZO JOSEPH-16,000--
2026-05-04LOSCALZO JOSEPH-12,000--
2026-05-04LOSCALZO JOSEPH-16,000--
2026-05-04LOSCALZO JOSEPH-10,321--
2026-05-04LOSCALZO JOSEPH-12,000--
2026-05-04LOSCALZO JOSEPH-10,968--
2026-05-04LOSCALZO JOSEPH-17,781$75.5826$1,343,934
2026-05-04LOSCALZO JOSEPH-59,508$74.9024$4,457,292
2026-05-04LOSCALZO JOSEPH+16,000$64.8$1,036,800
2026-05-04LOSCALZO JOSEPH+12,000$60.2$722,400
2026-05-04LOSCALZO JOSEPH+16,000$42.88$686,080
2026-05-04LOSCALZO JOSEPH+10,321$41.08$423,987
2026-05-04LOSCALZO JOSEPH+12,000$40.05$480,600
2026-05-04LOSCALZO JOSEPH+10,968$38.06$417,442
2026-05-01KLEIN JOSEPH III-10,111--
2026-05-01KLEIN JOSEPH III-1,431$74.4474$106,534
2026-05-01KLEIN JOSEPH III-8,680$73.353$636,704
2026-05-01KLEIN JOSEPH III+10,111$47.11$476,329
2026-04-28Baroldi Joseph-1,626$71.7877$116,727
2026-04-16Birchler Brian-973$75.042$73,016
2026-04-16Baroldi Joseph-5,619$74.56$418,953
2026-04-16Jenne Kyle-4,902$75.171$368,488
2026-04-15Birchler Brian-1,875--
2026-04-15Birchler Brian+1,875--
2026-04-15Baroldi Joseph-10,837--
2026-04-15Baroldi Joseph+10,837--
2026-04-15Jenne Kyle-12,226--
2026-04-15Jenne Kyle+12,226--
2026-04-15PARSHALL B LYNNE-534$76.97$41,102
2026-04-15PARSHALL B LYNNE-4,466$76.19$340,265
2026-04-02Devers Shannon L.-6,193$74.0535$458,613
2026-04-01KLEIN JOSEPH III-10,321--
2026-04-01KLEIN JOSEPH III-12,000--
2026-04-01KLEIN JOSEPH III-2,216$75.954$168,314
2026-04-01KLEIN JOSEPH III-20,105$75.503$1,517,988
2026-04-01KLEIN JOSEPH III+10,321$41.08$423,987
2026-04-01KLEIN JOSEPH III+12,000$38.06$456,720
2026-03-19Schneider Eugene-5,812$70.9715$412,486
2026-03-17HOUGEN ELIZABETH L-10,172$73.207$744,662
2026-03-16HOUGEN ELIZABETH L-60,299--
2026-03-16HOUGEN ELIZABETH L-61,041--
2026-03-16HOUGEN ELIZABETH L-20,541--
2026-03-16HOUGEN ELIZABETH L-33,118--
2026-03-16HOUGEN ELIZABETH L-9,440$72.765$686,902
2026-03-16HOUGEN ELIZABETH L-205,608$72.381$14,882,113
2026-03-16HOUGEN ELIZABETH L+20,541$37.58$771,931
2026-03-16HOUGEN ELIZABETH L+33,118$32.6$1,079,647
2026-03-16HOUGEN ELIZABETH L+61,041$56.78$3,465,908
2026-03-16HOUGEN ELIZABETH L+60,299$60.89$3,671,606
2026-03-10Jenne Kyle-32,602--
2026-03-10Jenne Kyle-4,675--
2026-03-10Jenne Kyle+4,675$34.69$162,176
2026-03-10Jenne Kyle-16,086$76.3$1,227,362
2026-03-10Jenne Kyle-21,191$75.502$1,599,963
2026-03-10Jenne Kyle+32,602$46.1$1,502,952
2026-03-10Monia Brett P-34,103--
2026-03-10Monia Brett P-17,591$76.3407$1,342,909
2026-03-10Monia Brett P-16,512$75.4745$1,246,235
2026-03-10Monia Brett P+34,103$60.89$2,076,532
2026-03-09O'NEIL PATRICK R.-10,148$75.2525$763,662
2026-03-09Monia Brett P-73,529--
2026-03-09Monia Brett P-40,822--
2026-03-09Monia Brett P-1,684$75.583$127,282
2026-03-09Monia Brett P-117,604$75.258$8,850,642
2026-03-09Monia Brett P-7,382$74.111$547,087
2026-03-09Monia Brett P+73,529$60.89$4,477,181
2026-03-09Monia Brett P+40,822$60.89$2,485,652
2026-03-04Baroldi Joseph-238--
2026-03-04Baroldi Joseph-201--
2026-03-04Baroldi Joseph-201$80$16,080
2026-03-04Baroldi Joseph+201$32.6$6,553
2026-03-04Baroldi Joseph-238$80$19,040
2026-03-04Baroldi Joseph+238$56.78$13,514
2026-03-04LOSCALZO JOSEPH-200--
2026-03-04LOSCALZO JOSEPH-200$80$16,000
2026-03-04LOSCALZO JOSEPH+200$38.06$7,612
2026-03-03Devers Shannon L.-385--
2026-03-03Devers Shannon L.-3,760--
2026-03-03Devers Shannon L.-3,510--
2026-03-03Devers Shannon L.-5,500--
2026-03-03Devers Shannon L.-6,951--
2026-03-03Devers Shannon L.-755$80.837$61,032
2026-03-03Devers Shannon L.-5,030$79.999$402,395
2026-03-03Devers Shannon L.-14,321$79.115$1,133,006
2026-03-03Devers Shannon L.+385$52.87$20,355
2026-03-03Devers Shannon L.+6,951$32.6$226,603
2026-03-03Devers Shannon L.+5,500$34.69$190,795
2026-03-03Devers Shannon L.+3,760$40.85$153,596
2026-03-03Devers Shannon L.+3,510$37.58$131,906
2026-03-03Baroldi Joseph-820--
2026-03-03Baroldi Joseph-879--
2026-03-03Baroldi Joseph-36$81.01$2,916
2026-03-03Baroldi Joseph-2,088$80.4079$167,892
2026-03-03Baroldi Joseph+879$32.6$28,655
2026-03-03Baroldi Joseph+820$56.78$46,560
2026-03-03Baroldi Joseph-4,096$79.36$325,059
2026-03-03Diaz Allene M.-10,321--
2026-03-03Diaz Allene M.-18,000--
2026-03-03Diaz Allene M.-12,000--
2026-03-03Diaz Allene M.-1,005$80.799$81,203
2026-03-03Diaz Allene M.-14,608$79.875$1,166,814
2026-03-03Diaz Allene M.-39,265$79.114$3,106,411
2026-03-03Diaz Allene M.+18,000$40.05$720,900
2026-03-03Diaz Allene M.+12,000$38.06$456,720
2026-03-03Diaz Allene M.+10,321$41.08$423,987
2026-03-03LOSCALZO JOSEPH-832--
2026-03-03LOSCALZO JOSEPH-832$80.3279$66,833
2026-03-03LOSCALZO JOSEPH+832$38.06$31,666
2026-03-03KLEIN JOSEPH III-4,000--
2026-03-03KLEIN JOSEPH III-12,000--
2026-03-03KLEIN JOSEPH III-1,012$80.818$81,788
2026-03-03KLEIN JOSEPH III-6,794$79.995$543,486
2026-03-03KLEIN JOSEPH III-13,526$79.174$1,070,908
2026-03-03KLEIN JOSEPH III+4,000$42.88$171,520
2026-03-03KLEIN JOSEPH III+12,000$40.05$480,600
2026-03-03BENNETT C FRANK-48,626--
2026-03-03BENNETT C FRANK-16,463--
2026-03-03BENNETT C FRANK-802$80.762$64,771
2026-03-03BENNETT C FRANK-12,687$79.8778$1,013,410
2026-03-03BENNETT C FRANK-71,600$79.099$5,663,488
2026-03-03BENNETT C FRANK+48,626$60.89$2,960,837
2026-03-03BENNETT C FRANK+16,463$32.6$536,694
2026-02-27Birchler Brian+351$48.8665$17,152
2026-02-27Swayze Eric+256$48.8665$12,510
2026-02-27O'NEIL PATRICK R.+376$48.8665$18,374
2026-02-27Monia Brett P+484$48.8665$23,651
2026-02-27BENNETT C FRANK+261$48.8665$12,754
2026-02-13Swayze Eric-6,207$82.0691$509,403
2026-02-13Swayze Eric-9,435$81.5592$769,511
2026-02-11PARSHALL B LYNNE-5,000$82.7177$413,588
2026-02-06Monia Brett P-29,430$85.7907$2,524,820
2026-02-02BENNETT C FRANK0--
2026-02-02BENNETT C FRANK-48,626--
2026-02-02BENNETT C FRANK-16,463--
2026-02-02BENNETT C FRANK-16,463$83.0284$1,366,897
2026-02-02BENNETT C FRANK+16,463$32.6$536,694
2026-02-02BENNETT C FRANK-48,626$83.0284$4,037,339
2026-02-02BENNETT C FRANK+48,626$60.89$2,960,837
2026-02-02BENNETT C FRANK-20,000$82.599$1,651,980
2026-01-30Birchler Brian-6,179$83.0309$513,048
2026-01-30Schneider Eugene-6,179$83.4487$515,630
2026-01-30Baroldi Joseph-5,296$82.9615$439,364
2026-01-30Swayze Eric-6,179$82.9335$512,446
2026-01-30O'NEIL PATRICK R.-6,179$83.5335$516,153
2026-01-30Monia Brett P-62,970$82.7216$5,208,979
2026-01-30HOUGEN ELIZABETH L-6,988$83.243$581,702
2026-01-30BENNETT C FRANK-5,885$82.9466$488,141
2026-01-29Birchler Brian+11,991--
2026-01-29Schneider Eugene+11,991--
2026-01-29Baroldi Joseph+10,278--
2026-01-29Swayze Eric+11,991--
2026-01-29O'NEIL PATRICK R.+11,991--
2026-01-29Monia Brett P+122,214--
2026-01-29HOUGEN ELIZABETH L+13,562--
2026-01-29BENNETT C FRANK+11,421--
2026-01-22Devers Shannon L.-3,977$81.3403$323,490
2026-01-16Kordasiewicz Holly B.-4,141$75.66$313,308
2026-01-16Devers Shannon L.-8,353$75.95$634,410
2026-01-16Birchler Brian-8,480$75.11$636,933
2026-01-16Schneider Eugene-9,302$75.59$703,138
2026-01-16Baroldi Joseph-1,149$75.78$87,071
2026-01-16Baroldi Joseph-6,907$75.75$523,205
2026-01-16Jenne Kyle-1,823$75.96$138,475
2026-01-16Swayze Eric-49$75.97$3,723
2026-01-16Swayze Eric-9,884$75.34$744,661
2026-01-16O'NEIL PATRICK R.-9,191$75.84$697,045
2026-01-16Monia Brett P-44,034$74.82$3,294,624
2026-01-16HOUGEN ELIZABETH L-12,922$75.22$971,993
2026-01-16BENNETT C FRANK-8,977$75.15$674,622
2026-01-15Kordasiewicz Holly B.+11,250--
2026-01-15Kordasiewicz Holly B.+13,650--
2026-01-15Kordasiewicz Holly B.-11,119--
2026-01-15Kordasiewicz Holly B.+11,119--
2026-01-15Devers Shannon L.+9,675--
2026-01-15Devers Shannon L.-17,377--
2026-01-15Devers Shannon L.+25,800--
2026-01-15Devers Shannon L.+17,377--
2026-01-15Birchler Brian+9,675--
2026-01-15Birchler Brian-20,089--
2026-01-15Birchler Brian+25,800--
2026-01-15Birchler Brian+20,089--
2026-01-15Schneider Eugene+9,675--
2026-01-15Schneider Eugene-21,685--
2026-01-15Schneider Eugene+25,800--
2026-01-15Schneider Eugene+21,685--
2026-01-15Baroldi Joseph+3,900--
2026-01-15Baroldi Joseph-2,850--
2026-01-15Baroldi Joseph+9,675--
2026-01-15Baroldi Joseph-17,037--
2026-01-15Baroldi Joseph+25,800--
2026-01-15Baroldi Joseph+2,850--
2026-01-15Baroldi Joseph+17,037--
2026-01-15Jenne Kyle-7,013--
2026-01-15Jenne Kyle+9,675--
2026-01-15Jenne Kyle+25,800--
2026-01-15Jenne Kyle+7,013--
2026-01-15Swayze Eric+225--
2026-01-15Swayze Eric-111--
2026-01-15Swayze Eric+9,675--
2026-01-15Swayze Eric-21,366--
2026-01-15Swayze Eric+25,800--
2026-01-15Swayze Eric+111--
2026-01-15Swayze Eric+21,366--
2026-01-15YANG MICHAEL J.-1,930--
2026-01-15YANG MICHAEL J.+1,930--
2026-01-15O'NEIL PATRICK R.+9,675--
2026-01-15O'NEIL PATRICK R.-21,473--
2026-01-15O'NEIL PATRICK R.+25,800--
2026-01-15O'NEIL PATRICK R.+21,473--
2026-01-15Monia Brett P+42,705--
2026-01-15Monia Brett P-89,145--
2026-01-15Monia Brett P+113,880--
2026-01-15Monia Brett P+89,145--
2026-01-15HOUGEN ELIZABETH L+12,885--
2026-01-15HOUGEN ELIZABETH L-28,729--
2026-01-15HOUGEN ELIZABETH L+34,360--
2026-01-15HOUGEN ELIZABETH L+28,729--
2026-01-15BENNETT C FRANK+9,675--
2026-01-15BENNETT C FRANK-21,055--
2026-01-15BENNETT C FRANK+25,800--
2026-01-15BENNETT C FRANK+21,055--
2026-01-07Devers Shannon L.-25,545--
2026-01-07Devers Shannon L.-9,264--
2026-01-07Devers Shannon L.-3,829--
2026-01-07Devers Shannon L.-3,460--
2026-01-07Devers Shannon L.-2,101--
2026-01-07Devers Shannon L.-9,264$84.62$783,920
2026-01-07Devers Shannon L.+9,264$52.87$489,788
2026-01-07Devers Shannon L.-3,829$84.62$324,010
2026-01-07Devers Shannon L.+3,829$37.58$143,894
2026-01-07Devers Shannon L.-3,460$84.62$292,785
2026-01-07Devers Shannon L.+3,460$32.6$112,796
2026-01-07Devers Shannon L.-2,101$85.36$179,341
2026-01-07Devers Shannon L.+2,101$32.6$68,493
2026-01-07Devers Shannon L.-25,545$85.36$2,180,521
2026-01-07Devers Shannon L.+25,545$56.78$1,450,445
2026-01-02Kordasiewicz Holly B.+7,500--
2026-01-02Schneider Eugene+19,350--
2026-01-02Kordasiewicz Holly B.+9,100--
2026-01-02Devers Shannon L.+19,350--
2026-01-02Birchler Brian+19,350--
2026-01-02Baroldi Joseph+2,600--
2026-01-02Baroldi Joseph+19,350--
2026-01-02Jenne Kyle+19,350--
2026-01-02Swayze Eric+150--
2026-01-02Swayze Eric+19,350--
2026-01-02Swayze Eric-18,338--
2026-01-02Swayze Eric-5,125--
2026-01-02Swayze Eric-18,338$79.27$1,453,653
2026-01-02Swayze Eric+18,338$60.89$1,116,601
2026-01-02Swayze Eric-5,125$78.57$402,671
2026-01-02Swayze Eric+5,125$60.89$312,061
2026-01-02O'NEIL PATRICK R.+19,350--
2026-01-02Monia Brett P+85,410--
2026-01-02HOUGEN ELIZABETH L+25,770--
2026-01-02BENNETT C FRANK+19,350--
2025-12-01WENDER JOSEPH H-7,429$81.2338$603,486
2025-12-01WENDER JOSEPH H-20,571$80.6651$1,659,362
2025-11-25Devers Shannon L.-16,777--
2025-11-25Devers Shannon L.-16,777$80.9109$1,357,442
2025-11-25Devers Shannon L.+16,777$53.77$902,099
2025-11-25KLEIN JOSEPH III-4,000--
2025-11-25KLEIN JOSEPH III-4,000--
2025-11-25KLEIN JOSEPH III-4,000--
2025-11-25KLEIN JOSEPH III-4,000$80$320,000
2025-11-25KLEIN JOSEPH III+4,000--
2025-11-25KLEIN JOSEPH III-4,000$80$320,000
2025-11-25KLEIN JOSEPH III+4,000--
2025-11-25KLEIN JOSEPH III-4,000$80$320,000
2025-11-25KLEIN JOSEPH III+4,000--
2025-11-19HERMAN JOAN E-32,000--
2025-11-19HERMAN JOAN E-12,000--
2025-11-19HERMAN JOAN E-32,000$72.1325$2,308,240
2025-11-19HERMAN JOAN E+32,000$63.9$2,044,800
2025-11-19HERMAN JOAN E-12,000$72.1325$865,590
2025-11-19HERMAN JOAN E+12,000$40.05$480,600
2025-11-18WENDER JOSEPH H-16,000--
2025-11-18WENDER JOSEPH H+16,000$24.42$390,720
2025-11-06Birchler Brian-8,000$76.1724$609,379
2025-11-06Geary Richard S-18,300--
2025-11-06Geary Richard S-14,738--
2025-11-06Geary Richard S-18,300$75.421$1,380,204
2025-11-06Geary Richard S+18,300$60.89$1,114,287
2025-11-06Geary Richard S-14,738$76.0972$1,121,521
2025-11-06Geary Richard S+14,738$56.78$836,824
2025-11-05Geary Richard S-801--
2025-11-05Geary Richard S-800--
2025-11-05Geary Richard S-801$75.01$60,083
2025-11-05Geary Richard S+801$60.89$48,773
2025-11-05Geary Richard S-800$75.01$60,008
2025-11-05Geary Richard S+800$56.78$45,424
2025-11-03Geary Richard S-775--
2025-11-03Geary Richard S-905--
2025-11-03Geary Richard S-905$75.054$67,924
2025-11-03Geary Richard S+905$56.78$51,386
2025-11-03Geary Richard S-775$75.054$58,167
2025-11-03Geary Richard S+775$60.89$47,190
2025-11-03Geary Richard S-905--
2025-11-03Geary Richard S-775--
2025-11-03Geary Richard S-905$75.054$67,924
2025-11-03Geary Richard S+905$60.89$55,105
2025-11-03Geary Richard S-775$75.054$58,167
2025-11-03Geary Richard S+775$56.78$44,005
2025-10-31Geary Richard S-34,585--
2025-10-31Geary Richard S-34,664--
2025-10-31Geary Richard S-20,000$75.1083$1,502,166
2025-10-31Geary Richard S-34,664$75.1083$2,603,554
2025-10-31Geary Richard S+34,664$56.78$1,968,222
2025-10-31Geary Richard S-34,585$75.1083$2,597,621
2025-10-31Geary Richard S+34,585$60.89$2,105,881
2025-10-31LOSCALZO JOSEPH-16,000--
2025-10-31LOSCALZO JOSEPH-16,000$75.1043$1,201,669
2025-10-31LOSCALZO JOSEPH+16,000$52.22$835,520
2025-10-31WENDER JOSEPH H-11,200$75.1586$841,776
2025-10-30WENDER JOSEPH H-5,975$73.85$441,254
2025-10-30WENDER JOSEPH H-8,341$73.16$610,228
2025-10-30WENDER JOSEPH H-2,484$72.19$179,320
2025-10-16Devers Shannon L.-1,263$73.6213$92,984
2025-10-16Swayze Eric-53$73.6213$3,902
2025-10-15Devers Shannon L.-2,820--
2025-10-15Devers Shannon L.-6,000--
2025-10-15Devers Shannon L.+2,820--
2025-10-15Devers Shannon L.-6,000$72.9423$437,654
2025-10-15Devers Shannon L.+6,000$48.51$291,060
2025-10-15Birchler Brian-12,425--
2025-10-15Birchler Brian-12,425$72.2252$897,398
2025-10-15Birchler Brian+12,425$53.77$668,092
2025-10-15Swayze Eric-125--
2025-10-15Swayze Eric+125--
2025-10-15PARSHALL B LYNNE-5,000$71.7443$358,722
2025-10-14Birchler Brian-11,475--
2025-10-14Birchler Brian-11,475$72.0339$826,589
2025-10-14Birchler Brian+11,475$53.77$617,011
2025-10-06Baroldi Joseph-1,625$69.3693$112,725
2025-10-06Swayze Eric-6,849$69.02$472,718
2025-10-06O'NEIL PATRICK R.-10,200--
2025-10-06O'NEIL PATRICK R.-3,241$69.2651$224,488
2025-10-06O'NEIL PATRICK R.-10,200$69.8872$712,849
2025-10-06O'NEIL PATRICK R.+10,200$52.87$539,274
2025-10-06Monia Brett P-437$69.2637$30,268